I-TASSER results

I-TASSER results for job id Rv0349

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (219 residues)
MPELETPDDPESIYLARLEDVGEHRPTFTGDIYRLGDGRMVMILQHPCALRHGVDLHPRL
LVAPVRPDSLRSNWARAPFGTMPLPKLIDGQDHSADFINLELIDSPTLPTCERIAVLSQS
GVNLVMQRWVYHSTRLAVPTHTYSDSTVGPFDEADLIEEWVTDRVDDGADPQAAEHECAS
WLDERISGRTRRALLSDRQHASSIRREARSHRKSVKLAD

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MPELETPDDPESIYLARLEDVGEHRPTFTGDIYRLGDGRMVMILQHPCALRHGVDLHPRLLVAPVRPDSLRSNWARAPFGTMPLPKLIDGQDHSADFINLELIDSPTLPTCERIAVLSQSGVNLVMQRWVYHSTRLAVPTHTYSDSTVGPFDEADLIEEWVTDRVDDGADPQAAEHECASWLDERISGRTRRALLSDRQHASSIRREARSHRKSVKLAD
Prediction	CCCCCCCCCHHHHHHHHCHHCCCCCCCEEEEEEEHCCCCEEEEEHCHHHHHCCCCCCCEEEEEHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEHCCCCCCCCCCEEEEHCHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
Conf.Score	998889998799999975545778875555789975895899986656655597544467776544554555666688888876566555554444443566478988766646764755668899888765556888755556655544677668999999876568885699999999998558996699998767889999999999988766659
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MPELETPDDPESIYLARLEDVGEHRPTFTGDIYRLGDGRMVMILQHPCALRHGVDLHPRLLVAPVRPDSLRSNWARAPFGTMPLPKLIDGQDHSADFINLELIDSPTLPTCERIAVLSQSGVNLVMQRWVYHSTRLAVPTHTYSDSTVGPFDEADLIEEWVTDRVDDGADPQAAEHECASWLDERISGRTRRALLSDRQHASSIRREARSHRKSVKLAD
Prediction	655274273143013233661554323121301434552100003220312562503220111403642456514614131120341142643224133023143461532530120344102000420242413000102313431333155152145105524655452363254025214663554434411544632443354146535646458
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCHHHHHHHHCHHCCCCCCCEEEEEEEHCCCCEEEEEHCHHHHHCCCCCCCEEEEEHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEHCCCCCCCCCCEEEEHCHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCC
MPELETPDDPESIYLARLEDVGEHRPTFTGDIYRLGDGRMVMILQHPCALRHGVDLHPRLLVAPVRPDSLRSNWARAPFGTMPLPKLIDGQDHSADFINLELIDSPTLPTCERIAVLSQSGVNLVMQRWVYHSTRLAVPTHTYSDSTVGPFDEADLIEEWVTDRVDDGADPQAAEHECASWLDERISGRTRRALLSDRQHASSIRREARSHRKSVKLAD

5jajA

0.12

0.95

0.66

MUSTER

TQKEAVYNKIMLSYLQKKLSGQRDLPQILGLTGTGGETSFEGAVEHILQICANLDTE---VIASAQQPTKQYDLCQEREQDPFGQRLKKIMAQIQEH-----MEMPELPQNFGTQVYEQRIVELENRAAERFCRKTVCALHLRRYNDALLINDTVRMMDAFQCLQQFYADKDPTERFLATTFEENR--ATLQALAGDQRYENPRLSKLEEILQEHFQGS

3sztA

0.12

0.11

0.95

0.56

dPPAS

LSRITTEEEFFSLVLEICGNYGFEFFSFGARAPFPLTAPKYHFLSYPGEWKSRYISEDYTSIDPIVRHGLLEYWNGEDFQEN---RFFWEEALHHGIRHGWSIPVRGKYGLISMLSLVRSSESIAATEILEKESFLLW--------ITSMLQATFGDLLAPRIVPESNVRLTARETEMLKWTAVGKTYGEIGLILSDQRTVKFHIVNAMRKLNSSNKAE

1jg6A2

0.19

0.15

0.79

0.58

wdPPAS

FP--------IEQYKIHMNDFQLSKPT-TLDVIYGGSFRS----QRESKMVEDTGLN-IEFFGNAREKNPKYPWTKAPFGKIPMNMVSEKNSQAIA---ALIIGDKNYNDN------------ITLRVWETMAS----------DAVMLIDEEFDTKHRIINDAR---VNNRAELIDRVNELKH--SDVLRKEMLS-IQHDILNKTRAKKAEWQDAFKK

4mvdB

0.14

0.13

0.94

0.57

wMUSTER

EVDFSKPYVRVTMEEAC-RGTPCERPVYADGIFDLFHSGHARALMQAKNLFPN-----TYLIVGV--CSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTRIDFVAHDDIDDVYKHIKEAF-ISTRIVRDYDVYARNLQRGYTAKELNVSFINEKK---YHLQERVDKVKKKVKDVEE--KSKEFVQKVEEKSIDLWEEKSREFIGSFLE

3tsaA2

0.20

0.15

0.72

0.60

wPPAS

VPY-NGSGAFP-AWGAA----RTSARRICG---------MVLNATGPAPLLRAVLPGVEAVIA---------PPEHALLTDLP--------------DNARIAEPLNLRTCE--LVICAGGSGTAFTATRL---QLVLP---YFD----QFDYARNLAAA------AGI-PDEQAQSDHEQFTD-----SIATVLGDAAAAIKLSDEITAMPHPAALVR

5fj8M

0.11

0.08

0.69

0.60

dPPAS2

--------------------IEEF------PLKISGEEESLHVFQYARLVGRKPAEHPFISAARYKPKSHLPLDEQAFYN------KDKAESEWNGVNVQTL-KGVGVENNGQYAAF------------VKDMQVYLVPIERVAQLKPFFKYIDDANVTRKQENRLTGSLLAHKVADEEANIEEGTFEQFKDTIVKE----------------------

3tsaA2

0.12

0.10

0.79

0.64

PPAS

VPY-NGSGAFPAWGAARTS-----ARRICGRMVLNATGPAPLL---RAVAAATELPGVEAVIAVPPEHRALLTDLPDNAESVPLNLF--------------------LRTCE--LVICAGGSGTAFTATRLGIPQLVLP----------QYFDQFDYARNLAAAGAGICLPDEQAQSDHEQFTD-----SIATVLGDTGFAAAAIKLSDEITAMPHPAA

3ia7A3

0.14

0.11

0.79

0.70

Env-PPAS

-P------GWQP--------PRPDAPVVSGNQFNEHPEFFRACAQ-AFA-----DTPWHVVAIGGFLDPAVLGPLPPNVEAHQIP-----FHS------V-------LAHAR--ACLTHGTTGAVLEAFAAGVPLVLVPHFATE-----AAPSAERVIELLGSVLRPDQLEPASIREAVERLAADSAVRERVRRQRDILSSGGPARAADEVEAYLGRVA

5dooA

0.08

0.07

0.96

0.60

MUSTER

INRKIEFDNLKDFYTTPENKIDLNNEQENISFYYENLPEPFISTTSAIMKAILYVYAENINPIRLEQVAKEAFKKLGKYRLQDFLATLEQHFITLIFQGYLKIFETKPHAIATITKTSQFARYQAKHAHFNNVTNMFSITNRLNDMIGIPIHEKYILEM-----LDGTHNIDDIKKSIIEKINSKLTACD----VTDPKLLKEFVDYVVAVSLEKFRIN

5iitA2

0.11

0.09

0.82

0.52

dPPAS

ENYDELVVKISQLYDIARTSGAGSDGFTVLSTKSLFLGQKLQVVQADIASIDSD-----AVVHPTNTDFYIGGEVGNTLEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSEKTVKNCLALADDKKKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSESIGIYVQEMAKL----------------------------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-4.42

Estimated TM-score = 0.25±0.07

Estimated RMSD = 16.4±3.0Å

Download Model 2

C-score=-4.83

Download Model 3

C-score=-4.73

Download Model 4

C-score=-4.46

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	2vg8A2	0.524	4.95	0.086	0.836
2	4rbnA3	0.518	5.20	0.067	0.840
3	3hbjA	0.518	4.90	0.066	0.794
4	2p6pA	0.517	4.80	0.073	0.781
5	2iyaA	0.514	4.36	0.076	0.740
6	3otgA	0.514	4.55	0.092	0.758
7	2c4mC	0.512	5.34	0.102	0.836
8	2iyfB	0.512	4.40	0.098	0.740
9	3s27A	0.510	5.36	0.063	0.836
10	3h4iA	0.510	4.63	0.094	0.753

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.11	5	1bcpC	ATP	Rep, Mult	205,206
2	0.02	1	2iyfB	UDP	Rep, Mult	33,34,64,98,100,119,123,125,128
3	0.02	1	2uxiA	G50	Rep, Mult	132,191
4	0.02	1	3gsiA	MG	Rep, Mult	31,161
5	0.02	1	4u5tA	3CG	Rep, Mult	205,212
6	0.02	1	4gszA	ZN	Rep, Mult	52,55
7	0.02	1	2akwB	MN	Rep, Mult	145,155,158
8	0.02	1	2q7sA	ZN	Rep, Mult	46,55,141
9	0.02	1	2y00A	2CV	Rep, Mult	194,200,204
10	0.02	1	1o5qA	MG	Rep, Mult	31,113
11	0.02	1	1kv8A	PO4	Rep, Mult	168,188,189
12	0.02	1	3jskC	FE2	Rep, Mult	93,185
13	0.02	1	4zb0A	FRU	Rep, Mult	197,198,199
14	0.02	1	3aj0A	ZN	Rep, Mult	46,57,132,155
15	0.02	1	1pnvB	UUU	Rep, Mult	2,3,14,106
16	0.02	1	3wmoP	BCL	Rep, Mult	217,218
17	0.02	1	2y02B	2CV	Rep, Mult	191,194,200
18	0.02	1	2wyiB	PG0	Rep, Mult	174,177

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2vg8A	0.523	5.31	0.092	0.849	2.4.1.218	121,143
2	0.060	1eg7A	0.480	5.81	0.057	0.840	6.3.4.3	NA
3	0.060	1ygpA	0.508	5.38	0.070	0.831	2.4.1.1	NA
4	0.060	1bu8A	0.453	5.93	0.035	0.794	3.1.1.3	NA
5	0.060	2c4mC	0.512	5.34	0.102	0.836	2.4.1.1	17
6	0.060	1l7aA	0.445	5.55	0.079	0.749	3.1.1.72,3.1.1.41	89
7	0.060	2qllA	0.495	5.27	0.032	0.804	2.4.1.1	NA
8	0.060	1y8zA	0.485	5.67	0.082	0.827	2.4.1.26	NA
9	0.060	1ahpA	0.508	5.35	0.112	0.831	2.4.1.1	25,134
10	0.060	2azdB	0.503	5.49	0.121	0.840	2.4.1.1	121
11	0.060	1sy7A	0.463	5.12	0.057	0.744	1.11.1.6	NA
12	0.060	2o6lB	0.461	4.23	0.059	0.648	2.4.1.17	121,132
13	0.060	3fvrA	0.452	5.41	0.093	0.753	3.1.1.6	89
14	0.060	2r60A	0.491	5.36	0.048	0.790	2.4.1.14	NA
15	0.060	2c1zA	0.489	4.89	0.054	0.758	2.4.1.115	121,145
16	0.060	2gejA	0.489	5.33	0.077	0.785	2.4.1.57	125
17	0.060	1l7qA	0.455	5.50	0.043	0.744	3.1.1.1	NA
18	0.060	2a3lA	0.471	5.56	0.030	0.781	3.5.4.6	NA
19	0.060	1gz5A	0.475	5.18	0.043	0.767	2.4.1.15	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.07	0.523	5.31	0.09	0.85	2vg8A	GO:0006805 GO:0008152 GO:0008194 GO:0009636 GO:0009651 GO:0009813 GO:0016740 GO:0016757 GO:0016758 GO:0035251 GO:0042178 GO:0043231 GO:0050505 GO:0052696 GO:0080043 GO:0080044
1	0.07	0.518	4.90	0.07	0.79	3hbjA	GO:0008152 GO:0009698 GO:0009813 GO:0016740 GO:0016757 GO:0016758
2	0.07	0.514	4.36	0.08	0.74	2iyaA	GO:0000166 GO:0008152 GO:0016740 GO:0016757 GO:0016758 GO:0016999
3	0.07	0.503	4.77	0.09	0.75	3ia7A	GO:0008152 GO:0016758 GO:0016999 GO:0046872
4	0.07	0.504	4.94	0.05	0.79	4relA	GO:0000166 GO:0008152 GO:0016740 GO:0016757 GO:0016758
5	0.07	0.489	4.89	0.05	0.76	2c1zA	GO:0008152 GO:0009718 GO:0016740 GO:0016757 GO:0016758 GO:0033303 GO:0033330 GO:0033485 GO:0047213
6	0.07	0.507	4.49	0.11	0.74	4m7pA	GO:0008152 GO:0016740 GO:0016757 GO:0016758 GO:0016999 GO:0046677
7	0.07	0.474	4.61	0.06	0.70	2o6lB	GO:0001972 GO:0005783 GO:0005789 GO:0006629 GO:0008152 GO:0008202 GO:0008209 GO:0009813 GO:0015020 GO:0016020 GO:0016021 GO:0016740 GO:0016757 GO:0016758 GO:0031090 GO:0043231 GO:0052695 GO:0052696 GO:0070062
8	0.06	0.501	5.04	0.05	0.79	2acvA	GO:0000166 GO:0008152 GO:0016740 GO:0016757 GO:0016758
9	0.06	0.494	4.75	0.07	0.75	2pq6A	GO:0008152 GO:0016740 GO:0016757 GO:0016758
10	0.06	0.264	6.43	0.04	0.51	3rpnA	GO:0004364 GO:0004602 GO:0005102 GO:0005622 GO:0005739 GO:0005743 GO:0005759 GO:0005777 GO:0006749 GO:0015035 GO:0016020 GO:0016740 GO:0030855 GO:0043231 GO:0055114 GO:0070062 GO:0098869 GO:1901687
11	0.06	0.308	5.27	0.01	0.51	3or5A	GO:0005623 GO:0016491 GO:0045454 GO:0055114
12	0.06	0.269	6.11	0.06	0.50	2l4hA	GO:0001525 GO:0001933 GO:0001934 GO:0001954 GO:0002931 GO:0005509 GO:0005634 GO:0005654 GO:0005737 GO:0005783 GO:0005794 GO:0005813 GO:0005815 GO:0005856 GO:0005886 GO:0006302 GO:0006469 GO:0006915 GO:0006974 GO:0007026 GO:0007049 GO:0007113 GO:0007155 GO:0007283 GO:0007286 GO:0008022 GO:0008284 GO:0008285 GO:0008427 GO:0010977 GO:0016020 GO:0016324 GO:0017016 GO:0019901 GO:0030027 GO:0030154 GO:0030220 GO:0030291 GO:0030307 GO:0030335 GO:0030424 GO:0030425 GO:0030426 GO:0031122 GO:0031982 GO:0032433 GO:0032587 GO:0033630 GO:0038163 GO:0042127 GO:0042383 GO:0042995 GO:0043005 GO:0043025 GO:0043066 GO:0043085 GO:0043495 GO:0044325 GO:0045653 GO:0046872 GO:0048471 GO:0051092 GO:0051301 GO:0051302 GO:0051898 GO:0070062 GO:0070374 GO:0070886 GO:0071356 GO:0071363 GO:0071901 GO:0071902 GO:0071944 GO:0090004 GO:0090050 GO:0090314 GO:0097191 GO:1900026 GO:1990090 GO:2000256
13	0.06	0.272	6.32	0.04	0.50	1cs6A	GO:0001764 GO:0005886 GO:0007155 GO:0007158 GO:0007409 GO:0007411 GO:0007417 GO:0016020 GO:0031225 GO:0050839 GO:0071205 GO:0097090
14	0.06	0.219	4.71	0.02	0.33	2lw4A	GO:0003676 GO:0003677 GO:0005634 GO:0005654 GO:0005813 GO:0006351 GO:0006354 GO:0006355 GO:0006357 GO:0008023 GO:0008270 GO:0032784 GO:0045944 GO:0046872
15	0.06	0.240	4.92	0.06	0.37	2e9kA	GO:0001947 GO:0003779 GO:0004497 GO:0005634 GO:0007010 GO:0007507 GO:0008270 GO:0010735 GO:0016491 GO:0016709 GO:0019417 GO:0030042 GO:0043914 GO:0046872 GO:0055114 GO:0071949
16	0.06	0.194	4.51	0.07	0.28	4v8mBZ	GO:0002181 GO:0003735 GO:0005840 GO:0006412 GO:0015934 GO:0022625 GO:0042273
17	0.06	0.195	5.44	0.04	0.33	4v8pBS	GO:0002181 GO:0003735 GO:0005622 GO:0005840 GO:0006412 GO:0015934 GO:0022625 GO:0030529 GO:0042273
18	0.06	0.223	3.62	0.09	0.29	3f51A	GO:0003677 GO:0043565

Consensus prediction of GO terms

Molecular Function	GO:0016757
GO-Score	0.58
Biological Processes	GO:0009813	GO:0016999	GO:0009636	GO:0042178	GO:0052696	GO:0009651	GO:0009698
GO-Score	0.13	0.13	0.07	0.07	0.07	0.07	0.07
Cellular Component	GO:0043231
GO-Score	0.07

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.