I-TASSER results

Input Sequence in FASTA format

>protein (246 residues)
MARSIPADRFSAIVAASARVFIAHGYQRTQVQDVADALALAKGTLYGYAQGKAALFAAAV
RYGDAQEALPLASELPVAAPVAGEIAAVVSARLAGEVTDMRLTHALRATLPPGATTGDAR
AELAGIVTDLYSRLARHRIALKLVDRCAPELPDLAEVWFGTGRNAQVDAVQAYLVHRERA
GLLILPGPAPMVARTIVELCALWAVHLHFDPSPEPWSIVQPGVIDDDAIAATLAEFVVRA
TTASSD

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MARSIPADRFSAIVAASARVFIAHGYQRTQVQDVADALALAKGTLYGYAQGKAALFAAAVRYGDAQEALPLASELPVAAPVAGEIAAVVSARLAGEVTDMRLTHALRATLPPGATTGDARAELAGIVTDLYSRLARHRIALKLVDRCAPELPDLAEVWFGTGRNAQVDAVQAYLVHRERAGLLILPGPAPMVARTIVELCALWAVHLHFDPSPEPWSIVQPGVIDDDAIAATLAEFVVRATTASSD
Prediction	CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
Conf.Score	998788999999999999999998986689999999989998999998899999999999999999999999986579999999999999999999856556788888754667647899999999999999999888889998876567768999999997899999999999999998999888758999999999999998876567887777654567788999999999987646787789
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MARSIPADRFSAIVAASARVFIAHGYQRTQVQDVADALALAKGTLYGYAQGKAALFAAAVRYGDAQEALPLASELPVAAPVAGEIAAVVSARLAGEVTDMRLTHALRATLPPGATTGDARAELAGIVTDLYSRLARHRIALKLVDRCAPELPDLAEVWFGTGRNAQVDAVQAYLVHRERAGLLILPGPAPMVARTIVELCALWAVHLHFDPSPEPWSIVQPGVIDDDAIAATLAEFVVRATTASSD
Prediction	765644751253015003500363215503043006306113200031163032002200430154025304521667440241023003300320144341120022214444425412520240034014202433221221242154123003201431244014201310330154131326521320031013102210132314354434533434222341013002400342455668
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MARSIPADRFSAIVAASARVFIAHGYQRTQVQDVADALALAKGTLYGYAQGKAALFAAAVRYGDAQEALPLASELPVAAPVAGEIAAVVSARLAGEVTDMRLTHALRATLPPGATTGDARAELAGIVTDLYSRLARHRIALKLVDRCAPELPDLAEVWFGTGRNAQVDAVQAYLVHRERAGLLILPGPAPMVARTIVELCALWAVHLHFDPSPEPWSIVQPGVIDDDAIAATLAEFVVRATTASSD

3bcgA

0.14

0.11

0.83

1.52

MUSTER

--KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE---------------------------------MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFD-----LKKEARDYVAILLEMYLLCTLRNPA-

5d18A

0.12

0.10

0.82

1.27

dPPAS

-----GERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITH---LLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEETHHH------------------------------------

5d18A

0.12

0.10

0.82

1.86

wdPPAS

-----GERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLE----DTTDVERMYRRLRQALEALIPVLLEETHHH------------------------------------

5d18A

0.15

0.12

0.82

1.85

wMUSTER

-----GERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHL--------------------------------LPSDIPPGKADL--VVAELTAFAVALSDGVYFAGHLE--PDTTDVERMYRRLRQALEALIPVLLEETHHH---

5d18A

0.15

0.12

0.82

2.37

wPPAS

-----GERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHL--------------------------------LPSDIPPGKADL--VVAELTAFAVALSDGVYFAGHLEP--DTTDVERMYRRLRQALEALIPVLLEETHHH---

5d18A

0.15

0.12

0.82

1.81

dPPAS2

-----GERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHL--------------------------------LPSDIPPGKADL--VVAELTAFAVALSDGVYFAGHL--EPDTTDVERMYRRLRQALEALIPVLLEETHHH---

5d18A

0.14

0.12

0.82

2.11

PPAS

-----GERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITH--------------------------------LLPSDIPPGKADL--VVAELTAFAVALSDGVYFAGHLEP--DTTDVERMYRRLRQALEALIPVLLEETHHH---

4w97A

0.14

0.11

0.79

2.92

Env-PPAS

VAGQV-NSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLAS-------------------------------------QPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRWYRPGG---PLT---AQQVGQQYLAIVLGGITKE-------

3himB

0.16

0.13

0.78

1.52

MUSTER

LGTS---KAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSLS--------------------------------------PEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFD-IEAAALAITSLGIDVSRWF------PSHTYSDPRIIAARYVELALRMVGC------AD

3bcgA

0.14

0.11

0.84

1.24

dPPAS

--KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF---------------------------------VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFD-----LKKEARDYVAILLEMYLLCPTLRNPA

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-1.02

Estimated TM-score = 0.59±0.14

Estimated RMSD = 8.0±4.4Å

Download Model 2

C-score=-1.75

Download Model 3

C-score=-2.96

Download Model 4

C-score=-2.06

Download Model 5

C-score=-4.55

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	5d18A	0.701	2.62	0.131	0.805
2	3e7qB	0.667	2.96	0.153	0.801
3	5d1rA	0.656	3.51	0.126	0.821
4	3bcgA	0.648	3.38	0.114	0.821
5	2qcoA	0.640	3.16	0.087	0.789
6	3lsjA	0.632	3.34	0.138	0.797
7	3lwjA	0.631	2.96	0.142	0.768
8	3c07A	0.629	3.43	0.131	0.780
9	2oi8A	0.626	2.96	0.111	0.756
10	2f07A	0.622	3.17	0.147	0.772

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.12	11	3btcA	MGR	Rep, Mult	67,96,99,110,127,130,131,197,198,201
2	0.08	7	5eyrA	5T0	Rep, Mult	71,74,84,85,88,89,92,130,133,136,197,200,229
3	0.07	6	2g0eD	CGQ	Rep, Mult	60,63,70,95,96,99,123,126,130
4	0.06	4	1jt0C	QNA	Rep, Mult	29,30,31,42,46,51,52
5	0.04	3	1jt0D	QNA	Rep, Mult	8,9,39,40,41,42,43,44,47,48
6	0.04	4	3whcA	ST9	Rep, Mult	59,60,63,64,67,92,95,102,105,106,110,120,123,124,127,128,131,193,197
7	0.03	3	3angD	DCC	Rep, Mult	16,20,24,25,27
8	0.02	2	3lsrA	QNA	Rep, Mult	2,30,31,32,36,42,43,46
9	0.01	1	2np5C	NDS	Rep, Mult	35,36,38,41
10	0.01	1	1u9oB	CNS	Rep, Mult	92,103,136,197,200,201,229
11	0.01	1	3iuv0	III	Rep, Mult	27,110,124,191,192,194,195,198,201,202,205,208,209,211,221,228,229,233
12	0.01	1	3btjB	DEQ	Rep, Mult	18,22,55,56
13	0.01	1	1rkwA	PNT	Rep, Mult	63,66,67,70,88,92,95,96,99,134,197,198

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2i2xA	0.459	5.59	0.093	0.744	2.1.1.90	21,25,57
2	0.060	2fhcA	0.424	5.29	0.052	0.654	3.2.1.41	75,175,188,192
3	0.060	3g0bB	0.434	5.65	0.076	0.703	3.4.14.5	NA
4	0.060	2z1qB	0.442	5.19	0.056	0.687	1.3.99.3	NA
5	0.060	2ix6E	0.435	5.24	0.028	0.671	1.3.3.6	102,126
6	0.060	1bucB	0.447	5.24	0.054	0.687	1.3.99.2	NA
7	0.060	2uxwA	0.451	4.88	0.041	0.675	1.3.99.-	NA
8	0.060	1wgzA	0.423	5.96	0.068	0.728	3.4.24.66	NA
9	0.060	2cseW	0.424	5.66	0.068	0.699	3.6.4.13	NA
10	0.060	2d0tB	0.476	5.81	0.066	0.793	1.13.11.52	NA
11	0.060	3mddA	0.451	5.05	0.035	0.683	1.3.99.3	65
12	0.060	1bf2A	0.424	5.76	0.049	0.720	3.2.1.68	NA
13	0.060	2ix6A	0.445	5.08	0.041	0.679	1.3.3.6	NA
14	0.060	2fhbA	0.424	5.25	0.048	0.654	3.2.1.41	NA
15	0.060	2wbiB	0.440	5.15	0.078	0.675	1.3.99.-	NA
16	0.060	1n63B	0.444	6.59	0.041	0.829	1.2.99.2	NA
17	0.060	3czkA	0.431	5.83	0.062	0.703	3.2.1.48	NA
18	0.060	2ebaA	0.446	5.12	0.097	0.687	1.3.99.7	57
19	0.060	2c6fA	0.458	6.25	0.072	0.785	3.4.15.1	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.34	0.586	3.60	0.18	0.76	3mnlA	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355 GO:0042803
1	0.33	0.573	3.75	0.11	0.76	1jt0A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0045892
2	0.30	0.544	3.66	0.16	0.70	2np3B	GO:0003677 GO:0006351 GO:0006355
3	0.29	0.571	3.48	0.13	0.73	3f1bA	GO:0003677 GO:0006351 GO:0006355
4	0.28	0.558	3.46	0.15	0.70	4aciB	GO:0000287 GO:0003677 GO:0006351 GO:0006355 GO:0046872
5	0.28	0.648	3.38	0.11	0.82	3bcgA	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0008144 GO:0042493 GO:0043565 GO:0045892
6	0.28	0.556	3.73	0.12	0.73	3vprA	GO:0003677 GO:0006351 GO:0006355 GO:0042802
7	0.27	0.605	3.50	0.12	0.78	2wuiA	GO:0003677 GO:0006351 GO:0006355
8	0.27	0.571	3.61	0.10	0.75	4l62A	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355
9	0.27	0.570	3.44	0.10	0.72	3on4A	GO:0003677 GO:0006351 GO:0006355
10	0.27	0.513	4.19	0.13	0.70	3b81A	GO:0003677 GO:0006351 GO:0006355
11	0.26	0.541	3.31	0.11	0.67	4hkuA	GO:0003677 GO:0006351 GO:0006355
12	0.26	0.589	3.52	0.11	0.75	3ppbA	GO:0003677 GO:0006351 GO:0006355
13	0.25	0.587	3.35	0.15	0.72	2hxoA	GO:0003677 GO:0006351 GO:0006355 GO:0045892
14	0.25	0.507	3.59	0.10	0.67	3egqA	GO:0003677 GO:0006351 GO:0006355
15	0.25	0.578	3.72	0.13	0.76	3pasB	GO:0003677 GO:0006351 GO:0006355
16	0.24	0.497	3.53	0.17	0.65	2qwtA	GO:0003677 GO:0006351 GO:0006355
17	0.24	0.581	2.68	0.14	0.68	3bniA	GO:0003677 GO:0006351 GO:0006355
18	0.24	0.547	3.65	0.16	0.71	3vuqC	GO:0003677 GO:0006351 GO:0006355
19	0.23	0.564	3.62	0.09	0.73	3geuA	GO:0003677 GO:0006351 GO:0006355
20	0.23	0.632	3.34	0.10	0.80	3vibC	GO:0003677 GO:0006351 GO:0006355
21	0.23	0.582	3.55	0.13	0.76	3c2bA	GO:0003677 GO:0006351 GO:0006355
22	0.22	0.586	3.27	0.13	0.72	3dcfA	GO:0003677 GO:0006351 GO:0006355
23	0.22	0.541	3.95	0.16	0.73	2of7A	GO:0003677 GO:0006351 GO:0006355
24	0.22	0.546	3.63	0.10	0.70	3ccyA	GO:0003677 GO:0006351 GO:0006355
25	0.22	0.582	3.49	0.14	0.75	4yzeA	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355 GO:0045892
26	0.22	0.631	3.42	0.12	0.80	3lhqA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
27	0.22	0.604	3.48	0.15	0.79	3qbmA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
28	0.21	0.570	3.56	0.12	0.72	2zcnD	GO:0003677 GO:0006351 GO:0006355
29	0.21	0.605	3.36	0.14	0.76	2hytA	GO:0003677 GO:0006351 GO:0006355
30	0.21	0.607	3.26	0.17	0.76	2g3bA	GO:0003677 GO:0006351 GO:0006355
31	0.21	0.539	3.89	0.11	0.71	2zozB	GO:0003677 GO:0006351 GO:0006355
32	0.20	0.607	3.43	0.13	0.77	4ichA	GO:0003677 GO:0006351 GO:0006355
33	0.20	0.575	3.71	0.12	0.75	2y31A	GO:0003677 GO:0006351 GO:0006355 GO:0045892
34	0.20	0.594	3.43	0.14	0.76	2genA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
35	0.20	0.509	3.88	0.08	0.66	2iaiA	GO:0003677 GO:0006351 GO:0006355
36	0.20	0.542	3.87	0.10	0.72	3dewA	GO:0003677 GO:0006351 GO:0006355 GO:0016020 GO:0016021
37	0.20	0.574	3.80	0.20	0.76	3cwrA	GO:0003677 GO:0006351 GO:0006355
38	0.20	0.577	3.58	0.10	0.75	3he0C	GO:0003677 GO:0006351 GO:0006355
39	0.20	0.644	3.17	0.09	0.79	3hggA	GO:0003677 GO:0006351 GO:0006355
40	0.20	0.611	3.68	0.17	0.78	4cgrA	GO:0003677 GO:0006351 GO:0006355
41	0.19	0.701	2.62	0.13	0.80	5d18A	GO:0003677 GO:0006351 GO:0006355
42	0.19	0.632	3.34	0.14	0.80	3lsjA	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355 GO:0045922
43	0.19	0.555	3.84	0.13	0.74	3cdlB	GO:0003677 GO:0006351 GO:0006355
44	0.19	0.546	3.88	0.10	0.72	1z0xA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677
45	0.19	0.568	3.60	0.09	0.74	3qkxA	GO:0003677 GO:0006351 GO:0006355
46	0.18	0.558	3.86	0.08	0.74	4auxA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
47	0.18	0.530	4.22	0.08	0.73	4me9A	GO:0003677 GO:0006351 GO:0006355
48	0.17	0.581	3.29	0.14	0.72	3htaA	GO:0003677 GO:0006351 GO:0006355
49	0.17	0.609	3.57	0.12	0.78	2id6A	GO:0003677 GO:0006351 GO:0006355
50	0.17	0.530	4.07	0.07	0.72	4pxiB	GO:0003677 GO:0006351 GO:0006355
51	0.17	0.549	4.27	0.12	0.76	4nn1A	GO:0003677 GO:0003700 GO:0006351 GO:0006355
52	0.17	0.545	4.18	0.09	0.74	3gziA	GO:0003677 GO:0006351 GO:0006355
53	0.17	0.589	3.65	0.16	0.78	3eupA	GO:0003677 GO:0006351 GO:0006355
54	0.17	0.559	3.81	0.11	0.74	4mxmA	GO:0003677 GO:0006351 GO:0006355
55	0.16	0.546	3.88	0.07	0.72	4w97A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0010468 GO:0019217
56	0.16	0.626	2.94	0.14	0.76	3whcA	GO:0003677 GO:0005737 GO:0006351 GO:0006355 GO:0006629 GO:0006631 GO:0016042
57	0.16	0.565	3.70	0.09	0.74	4mk6A	GO:0003677 GO:0006351 GO:0006355
58	0.15	0.524	3.85	0.10	0.69	3colA	GO:0003677 GO:0006351 GO:0006355
59	0.15	0.644	3.02	0.13	0.78	3lwjA	GO:0003677 GO:0006351 GO:0006355
60	0.15	0.608	3.85	0.13	0.78	3npiA	GO:0003677 GO:0006351 GO:0006355
61	0.14	0.631	3.21	0.18	0.80	3bhqA	GO:0003677 GO:0006351 GO:0006355
62	0.14	0.517	3.88	0.06	0.69	2ibdA	GO:0003677 GO:0006351 GO:0006355
63	0.13	0.619	3.45	0.14	0.77	5h9tH	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355 GO:0051051
64	0.13	0.532	4.20	0.12	0.72	5d1wD	GO:0003677 GO:0006351 GO:0006355
65	0.12	0.527	4.15	0.09	0.73	3nnrA	GO:0003677 GO:0006351 GO:0006355
66	0.11	0.586	3.05	0.16	0.72	4jl3C	GO:0003677 GO:0006351 GO:0006355
67	0.09	0.601	3.27	0.14	0.75	2zcxA	GO:0003677 GO:0006351 GO:0006355
68	0.09	0.622	3.51	0.12	0.80	2uxhA	GO:0003677 GO:0006351 GO:0006355
69	0.09	0.576	3.47	0.14	0.73	3himB	GO:0003677 GO:0006351 GO:0006355
70	0.08	0.560	3.69	0.14	0.74	3bruA	GO:0003677 GO:0006351 GO:0006355
71	0.08	0.557	3.61	0.07	0.71	3frqA	GO:0003677 GO:0006351 GO:0006355 GO:0016740
72	0.08	0.567	3.24	0.10	0.71	3knwA	GO:0003677 GO:0006351 GO:0006355
73	0.08	0.645	3.40	0.13	0.80	3c07A	GO:0003677 GO:0006351 GO:0006355
74	0.08	0.565	3.65	0.09	0.73	2g7sA	GO:0003677 GO:0006351 GO:0006355
75	0.08	0.563	3.09	0.11	0.69	2eh3A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0046872
76	0.07	0.599	3.68	0.14	0.77	3p9tA	GO:0003677 GO:0006351 GO:0006355
77	0.07	0.525	3.47	0.13	0.67	2fd5A	GO:0003677 GO:0003700 GO:0006351 GO:0006355
78	0.07	0.566	3.76	0.16	0.76	3dpjA	GO:0003677 GO:0006351 GO:0006355
79	0.07	0.559	3.26	0.09	0.70	1sgmA	GO:0003677 GO:0006351 GO:0006355
80	0.07	0.502	3.98	0.10	0.68	3kkcA	GO:0003677 GO:0006351 GO:0006355
81	0.07	0.550	3.80	0.08	0.73	2vprA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
82	0.07	0.541	3.83	0.10	0.71	2raeA	GO:0003677 GO:0006351 GO:0006355
83	0.07	0.553	4.26	0.09	0.76	3nrgA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
84	0.07	0.525	4.30	0.08	0.72	2qtqA	GO:0003677 GO:0006351 GO:0006355
85	0.07	0.519	4.52	0.12	0.76	2fbqA	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355 GO:0044212 GO:0045893 GO:0050714
86	0.07	0.532	4.32	0.09	0.74	3s5rA	GO:0003677 GO:0006351 GO:0006355
87	0.07	0.508	3.67	0.12	0.67	2guhA	GO:0003677 GO:0006351 GO:0006355
88	0.07	0.513	4.36	0.10	0.73	3rh2A	GO:0003677 GO:0006351 GO:0006355
89	0.07	0.466	4.60	0.06	0.65	2i10B	GO:0003677 GO:0006351 GO:0006355

Consensus prediction of GO terms

Molecular Function	GO:0046872	GO:0003700	GO:0000976	GO:0042803
GO-Score	0.57	0.56	0.34	0.34
Biological Processes	GO:0045892
GO-Score	0.33
Cellular Component	GO:0005829
GO-Score	0.34

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv0330c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]