I-TASSER results

Input Sequence in FASTA format

>protein (208 residues)
MRLTHPARRYLSSQAARPTGAFGRLLGRIWRAETADVNRIAVELLAPGPGERVCEIGFGP
GRTLGLLAAAGAQVSGVEVSTTMIAIAAHHNAKAIAAGLISLYHGDGVTLPVADHSLDKV
LGVHNFYFWPDPRASLCDIARALRPGGRLVLTSISDDQPLAARFDPAIYRVPPTLDTAAW
LGAAGFIDVGIKRSADHPATVWFTATAT

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MRLTHPARRYLSSQAARPTGAFGRLLGRIWRAETADVNRIAVELLAPGPGERVCEIGFGPGRTLGLLAAAGAQVSGVEVSTTMIAIAAHHNAKAIAAGLISLYHGDGVTLPVADHSLDKVLGVHNFYFWPDPRASLCDIARALRPGGRLVLTSISDDQPLAARFDPAIYRVPPTLDTAAWLGAAGFIDVGIKRSADHPATVWFTATAT
Prediction	CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEHCCCCCHHHHHHHHHCCEEEEEHCCHHHHHHHHHHHHHHCCCCCEEEEHCCHHHCCCCCCCCCEEEEHCCHHHCCCHHHHHHHHHHHCCCCCEEEEEHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEEHCCCCCCCEEEEEHC
Conf.Score	9876999999999976865477888888865765699999999969999976999779998899999997998999969999999999999997887986999956666999988654798864545488999999999998589978999986899756667777665589999999999998995799999578877665899979
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MRLTHPARRYLSSQAARPTGAFGRLLGRIWRAETADVNRIAVELLAPGPGERVCEIGFGPGRTLGLLAAAGAQVSGVEVSTTMIAIAAHHNAKAIAAGLISLYHGDGVTLPVADHSLDKVLGVHNFYFWPDPRASLCDIARALRPGGRLVLTSISDDQPLAARFDPAIYRVPPTLDTAAWLGAAGFIDVGIKRSADHPATVWFTATAT
Prediction	8734551252037205313320030013113433340142015207153543041011202300220063404010011145005302631574446530302201035041367131000000001104314300310241523400000000145531342234102311325202400570554404244366442310020128
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEHCCCCCHHHHHHHHHCCEEEEEHCCHHHHHHHHHHHHHHCCCCCEEEEHCCHHHCCCCCCCCCEEEEHCCHHHCCCHHHHHHHHHHHCCCCCEEEEEHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEEEHCCCCCCCEEEEEHC
MRLTHPARRYLSSQAARPTGAFGRLLGRIWRAETADVNRIAVELLAPGPGERVCEIGFGPGRTLGLLAAAGAQVSGVEVSTTMIAIAAHHNAKAIAAGLISLYHGDGVTLPVADHSLDKVLGVHNFYFWPDPRASLCDIARALRPGGRLVLTSISDDQPLAARFDPAIYRVPPTLDTAAWLGAAGFIDVGIKRSADHPATVWFTATAT

4ineA2

0.19

1.00

1.86

MUSTER

TDATITFRDFLDKTQNTGIDAYEWMFGVNFIGGYDENLKIIKRFGDFKPGQTMLDIGVGIGGGARQVADEFGHVHGIDLSSNMLAIALERLHEEKD-SRVKYSITDALVYQFEDNSFDYVFSRDCIQHIPDTEKLFSRIYKALKPGGKVLITMYGKGYKFKTYVAQRAYFLKNLKEIADIANKTGFVNVQTENMTPRFKEILLEERGH

3dh0B

0.15

0.13

0.90

2.80

dPPAS

---------------AHKFDPSKIKKLDDPSRLELFDPEKVLKEFGLKEGMTVLDVGTGAGFYLPYLSKMVGKVYAIDVQEEMVNYAWEKVNKLGL-KNVEVLKSEENKIPLPDNTVDFIFMAFTFHELSEPLKFLEELKRVAKPFAYLAIIDWKKEERDKG---PPPEEVYSEWEVGLILEDAGIRVGRVVEVGKYCFGVYAMIV--

4obwA

0.14

0.12

0.91

2.99

wdPPAS

-----------------VANRYDLMNDVMSLGIHRLWKDHFINKLNSTTPLNFIDVAGGSGDIAFGLLDHASTMDIVDINPDMLKEGEKRAMEQGKDPRVRFLVSNGEKLEEIDDSKDIYTVSFGIRNFTDIQKGLNTAYRVLKPGGIFYCLEFSKIEDSYQYLVESIERFPDQETFKSMIEKAGFKSAGYESLTFGICAIHWGIKV-

3dlcA

0.18

0.16

0.93

2.58

wMUSTER

NK----------KKFDKKGAKNDEISKTLFAPIYPIIAENIINRFGITAG-TCIDIGSGPGALSIALAKQSFSIRALDFSKH-NEIALKNIADANLNDRIQIVQGDVHNIPIEDNYADLIVSRGSVFFWEDVATAFREIYRILKSGGKTYIGGGFGNNPDWKEFNRKNISQENVERFQNVLDEIGISSYEIILGDEG---FWIIISKT

3dlcA

0.15

0.14

0.94

2.89

wPPAS

-------GSENKKKFDKKGAKNDEISKTLFAPIYPIIAENIINRFGITAG-TCIDIGSGPGALSIALAKQSDSIRALDFSKHNEIALKNIADAN-LNDRIQIVQGDVHNIPIEDNYADLIVSRGSVFFWEDVATAFREIYRILKSGGKTYIGGGFGNNPDWKEFNRKNISQENVERFQNVLDEIGISSYEIILGDEG---FWIIISKT

3dh0B

0.15

0.13

0.88

3.22

dPPAS2

------------------AHKFDPSKIKKLDRLELFDPEKVLKEFGLKEGMTVLDVGTGAGFYLPYLSKMVGKVYAIDVQEEMVNYAWEKVNKLGL-KNVEVLKSEENKIPLPDNTVDFIFMAFTFHELSEPLKFLEELKRVAKPFAYLAIIDWKKEERDKG---PPPEEVYSEWEVGLILEDAGIRVGRVVEVGKY---CFGVYAMI

3dlcA

0.16

0.15

0.94

2.57

PPAS

-------GSENKKKFDKKGAKNDEISKTLFAPIYPIIAENIINRFGITAG-TCIDIGSGPGALSIALAKQSFSIRALDFSKHNEIALKNIADANL-NDRIQIVQGDVHNIPIEDNYADLIVSRGSVFFWEDVATAFREIYRILKSGGKTYIGGGFGNKELRDSISAEIRKNPNVERFQNVLDEIGISSYEIILGDE----FWIIISKT

3dlcA

0.16

0.15

0.94

2.73

Env-PPAS

---GSENKKKFDKKGA----KNDEISKTLFAPIYPIIAENIINRFGITAG-TCIDIGSGPGALSIALAKQSFSIRALDFSKHNEIALKNIADANL-NDRIQIVQGDVHNIPIEDNYADLIVSRGSVFFWEDVATAFREIYRILKSGGKTYIGGGFGNKELRDSISAEIRKNPNVERFQNVLDEIGISSYEIILGDEG---FWIIISKT

4ineA

0.19

1.00

1.84

MUSTER

TDATITFRDFLDKTQNTGIDAYEWMFGVNFIGGYDENLKIIKRFGDFKPGQTMLDIGVGIGGGARQVADEFGHVHGIDLSSNMLAIALERLHEEKD-SRVKYSITDALVYQFEDNSFDYVFSRDCIQHIPDTEKLFSRIYKALKPGGKVLITMYGKGYKFKTYVAQRAYFLKNLKEIADIANKTGFVNVQTENMTPRFKEILLEERGH

3dlcA

0.16

0.15

0.94

2.77

dPPAS

-------GSENKKKFDKKGAKNDEISKTLFAPIYPIIAENIINRFGITAG-TCIDIGSGPGALSIALAKQDFSIRALDFSKHNEIALKNIADAN-LNDRIQIVQGDVHNIPIEDNYADLIVSRGSVFFWEDVATAFREIYRILKSGGKTYIGGGFGNKELRDSISAEIRKNPNVERFQNVLDEIGISSYEIILGD---EGFWIIISKT

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.22

Estimated TM-score = 0.69±0.12

Estimated RMSD = 5.9±3.7Å

Download Model 2

C-score=-0.88

Download Model 3

C-score=-0.86

Download Model 4

C-score=-2.04

Download Model 5

C-score=-3.16

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4pneA	0.824	2.60	0.193	0.942
2	3dlcA	0.801	2.75	0.169	0.923
3	3vc1A	0.800	3.31	0.107	0.971
4	3dh0B	0.799	2.05	0.171	0.894
5	4ineA	0.798	3.18	0.180	0.962
6	5egpA	0.790	2.63	0.120	0.923
7	4iv0A	0.784	3.00	0.149	0.938
8	4krgA	0.782	3.08	0.185	0.962
9	4obwA	0.778	2.54	0.148	0.909
10	4krhA	0.777	3.25	0.190	0.947

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.65	125	3ou6A	SAM	Rep, Mult	11,15,22,57,58,59,63,78,79,80,83,105,106,107,108,123,124,125
2	0.04	9	4er6A	AW2	Rep, Mult	41,55,57,58,59,63,78,79,80,105,106,107,121,124,128,150,151,202
3	0.02	5	1d2hA	SAH	Rep, Mult	78,79,80,83,105,106,107,125,128
4	0.01	2	5dsxA	5EW	Rep, Mult	34,37,38,41,55,58,63,121,122,124,126,150,151,152,200,201,202
5	0.01	3	3uj9A	PC	Rep, Mult	9,10,18,30,124,154,163,167,169
6	0.01	3	2o06A	MG	Rep, Mult	45,118,146,147
7	0.01	3	5drtA	5EG	Rep, Mult	23,27,34,55,57,58,59,60,62,63,121,122,124,150,151,152,202
8	0.00	1	4fsdA	CA	Rep, Mult	157,158
9	0.00	1	3dtnA	CA	Rep, Mult	81,104
10	0.00	1	1p91A	SAM	Rep, Mult	26,31,57,58,59,60,61,62,63,123,124,153,154,158,159,200

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.242	2iftA	0.600	3.13	0.071	0.740	2.1.1.52	72
2	0.214	3bgdA	0.713	3.33	0.144	0.899	2.1.1.67	22,103
3	0.213	2h11B	0.716	3.38	0.149	0.899	2.1.1.67	19
4	0.207	3lccA	0.726	3.15	0.124	0.889	2.1.1.-	57,101
5	0.160	3e05D	0.661	2.71	0.121	0.784	2.1.1.132	102
6	0.133	2ex4A	0.762	3.25	0.114	0.938	2.1.1.-	NA
7	0.111	1wznA	0.771	2.92	0.161	0.899	2.1.1.-	NA
8	0.108	3hnrA	0.680	3.02	0.187	0.817	2.1.1.-	NA
9	0.096	1f38A	0.654	2.75	0.146	0.784	2.1.1.-	NA
10	0.096	3bwmA	0.666	3.27	0.133	0.827	2.1.1.6	NA
11	0.093	2cl5A	0.667	3.24	0.139	0.827	2.1.1.6	NA
12	0.091	1xcjA	0.704	3.43	0.158	0.889	2.1.1.2	58,127
13	0.089	3e05B	0.660	2.79	0.125	0.788	2.1.1.132	109
14	0.084	3grzB	0.648	2.64	0.124	0.764	2.1.1.-	NA
15	0.060	1tw2B	0.759	3.25	0.156	0.938	2.1.1.-	NA
16	0.060	1kpiA	0.757	3.26	0.144	0.928	2.1.1.79	NA
17	0.060	3c6mD	0.693	3.64	0.134	0.889	2.5.1.22	25,41
18	0.060	2a14A	0.745	3.37	0.142	0.942	2.1.1.49	57,59
19	0.060	3c6kD	0.688	3.65	0.140	0.885	2.5.1.22	NA
20	0.060	2vdwG	0.750	2.99	0.094	0.918	2.7.7.50	84,127
21	0.060	1fp1D	0.705	3.15	0.135	0.861	2.1.1.-	NA
22	0.060	2iipA	0.757	3.35	0.129	0.947	2.1.1.1	57,59,106
23	0.060	1jq3A	0.687	3.30	0.104	0.870	2.5.1.16	57,79
24	0.060	1p91A	0.689	3.13	0.156	0.841	2.1.1.51	NA
25	0.060	1mjfA	0.668	3.71	0.146	0.880	2.5.1.16	57,78
26	0.060	1uirB	0.684	3.50	0.119	0.875	2.5.1.16	136
27	0.060	2i62C	0.746	3.24	0.127	0.933	2.1.1.1	18,57,59,106
28	0.060	1l1eA	0.725	3.11	0.138	0.880	2.1.1.79	NA
29	0.060	2pxxA	0.728	2.94	0.145	0.856	3.4.24.71	NA
30	0.060	2opbB	0.749	3.43	0.131	0.957	2.1.1.28	18,57,59
31	0.060	1kpgA	0.741	3.22	0.152	0.904	2.1.1.79	134
32	0.060	1kywC	0.717	3.19	0.099	0.885	2.1.1.68	NA
33	0.060	3i58A	0.758	3.11	0.131	0.923	2.1.1.-	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.41	0.754	2.72	0.24	0.88	1vlmA	GO:0005737 GO:0008152 GO:0008168 GO:0008757 GO:0032259
1	0.39	0.795	3.17	0.17	0.96	4krhA	GO:0008152 GO:0008168 GO:0032259 GO:0046872 GO:0051536 GO:0051539
2	0.34	0.743	3.11	0.18	0.89	2yqzA	GO:0008152 GO:0008168 GO:0032259 GO:0046872 GO:0051536 GO:0051539
3	0.34	0.811	2.69	0.17	0.93	3dlcA	GO:0008152 GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
4	0.33	0.771	2.92	0.16	0.90	1wznA
5	0.32	0.673	3.22	0.17	0.82	4rsrA	GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
6	0.32	0.680	3.02	0.19	0.82	3hnrA	GO:0008152 GO:0008168 GO:0008757 GO:0016740 GO:0032259
7	0.31	0.730	2.41	0.17	0.84	4qtuB	GO:0000056 GO:0000447 GO:0005634 GO:0005730 GO:0005737 GO:0006364 GO:0008152 GO:0008168 GO:0008757 GO:0016435 GO:0016740 GO:0032259 GO:0070476
8	0.31	0.724	2.71	0.29	0.86	2gs9A	GO:0008152 GO:0008168 GO:0032259
9	0.30	0.757	3.22	0.19	0.93	4necB	GO:0008168 GO:0016740 GO:0032259
10	0.30	0.799	2.05	0.17	0.89	3dh0B	GO:0005737 GO:0008757 GO:0032259 GO:0046872 GO:0051536 GO:0051539
11	0.30	0.798	3.18	0.18	0.96	4ineA	GO:0000773 GO:0005737 GO:0006656 GO:0008152 GO:0008168 GO:0016740 GO:0032259 GO:0080101
12	0.30	0.720	2.50	0.20	0.83	3egeA	GO:0008152 GO:0008168 GO:0032259
13	0.29	0.661	3.03	0.18	0.78	3cggA	GO:0008168 GO:0016740 GO:0032259
14	0.28	0.755	2.88	0.20	0.89	3d2lC	GO:0008168 GO:0016740 GO:0032259
15	0.28	0.651	2.94	0.14	0.76	5cm2Z	GO:0000049 GO:0002098 GO:0005634 GO:0005737 GO:0005829 GO:0008152 GO:0008168 GO:0008198 GO:0016300 GO:0016706 GO:0030488 GO:0032259 GO:0055114
16	0.28	0.825	2.58	0.19	0.94	4pneB	GO:0008152 GO:0008168 GO:0016740 GO:0032259
17	0.28	0.716	3.48	0.18	0.89	3h2bB	GO:0008168 GO:0016740 GO:0032259
18	0.28	0.799	3.25	0.11	0.97	3vc1D	GO:0008152 GO:0008168 GO:0008169 GO:0008757 GO:0016740 GO:0032259 GO:0042214
19	0.26	0.725	3.11	0.14	0.88	1l1eA	GO:0005737 GO:0006629 GO:0008168 GO:0008610 GO:0008825 GO:0009405 GO:0016740 GO:0032259 GO:0042783 GO:0046500 GO:0052167 GO:0071768
20	0.26	0.621	2.85	0.19	0.75	3fycA	GO:0000154 GO:0000179 GO:0003723 GO:0005737 GO:0006364 GO:0008168 GO:0008649 GO:0016433 GO:0016740 GO:0031167 GO:0032259
21	0.26	0.752	3.09	0.15	0.90	2avnA	GO:0008152 GO:0008168 GO:0016740 GO:0032259
22	0.26	0.767	2.99	0.13	0.91	1ve3B	GO:0046872 GO:0051536 GO:0051539
23	0.25	0.709	2.65	0.16	0.81	2gluA	GO:0005737 GO:0008152 GO:0008168 GO:0008757 GO:0016740 GO:0032259
24	0.24	0.749	3.04	0.21	0.88	3busA	GO:0008152 GO:0008168 GO:0016740 GO:0032259
25	0.24	0.770	2.80	0.18	0.92	5je1A	GO:0008168 GO:0016740 GO:0032259
26	0.24	0.764	3.19	0.15	0.93	1tpyA	GO:0005618 GO:0005737 GO:0005886 GO:0006629 GO:0008168 GO:0008610 GO:0008825 GO:0016740 GO:0032259 GO:0071768
27	0.23	0.784	2.88	0.15	0.93	3uj7A	GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
28	0.23	0.660	3.08	0.21	0.79	3ccfB	GO:0008152 GO:0008168 GO:0016740 GO:0030798 GO:0032259
29	0.23	0.654	2.75	0.15	0.78	1f38A	GO:0006479 GO:0008168 GO:0008276 GO:0009236 GO:0016740 GO:0032259 GO:0046140
30	0.22	0.696	2.78	0.16	0.81	1vl5A	GO:0008152 GO:0008168 GO:0016740 GO:0032259
31	0.21	0.754	3.32	0.13	0.94	4gekG	GO:0002098 GO:0008168 GO:0016300 GO:0016740 GO:0016743 GO:0030488 GO:0032259 GO:1904047
32	0.21	0.728	3.24	0.14	0.89	3f4kA	GO:0005737 GO:0008168 GO:0008757 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
33	0.20	0.774	2.82	0.19	0.92	4qdkA	GO:0005737 GO:0008168 GO:0008757 GO:0015979 GO:0015995 GO:0016740 GO:0032259 GO:0036068 GO:0046406
34	0.19	0.732	3.24	0.15	0.90	3kkzA	GO:0046872 GO:0051536 GO:0051539
35	0.18	0.727	3.15	0.13	0.89	3e7pA	GO:0046872 GO:0051536 GO:0051539
36	0.17	0.643	3.03	0.12	0.77	4hg2B	GO:0008152 GO:0008168 GO:0016740 GO:0032259
37	0.17	0.703	3.27	0.17	0.86	1p91A	GO:0005737 GO:0006364 GO:0008168 GO:0008270 GO:0008989 GO:0016740 GO:0032259 GO:0046872 GO:0052911 GO:0070475
38	0.17	0.798	3.19	0.11	0.96	4f86A	GO:0008168 GO:0008169 GO:0008757 GO:0016740 GO:0032259 GO:0042214
39	0.17	0.785	3.19	0.15	0.95	4mwzB	GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
40	0.16	0.577	3.14	0.14	0.73	1yubA	GO:0000154 GO:0000179 GO:0003723 GO:0008168 GO:0008649 GO:0016740 GO:0031167 GO:0032259 GO:0046677 GO:0052910
41	0.16	0.532	4.04	0.17	0.72	4dzrA	GO:0003676 GO:0006479 GO:0008168 GO:0008276 GO:0016740 GO:0018364 GO:0032259 GO:0036009 GO:0046872
42	0.14	0.764	3.34	0.15	0.94	1kpgA	GO:0005737 GO:0005886 GO:0006629 GO:0008168 GO:0008610 GO:0008825 GO:0016740 GO:0032259 GO:0046500 GO:0071768
43	0.11	0.653	2.40	0.13	0.76	3i9fB	GO:0008152 GO:0008168 GO:0032259 GO:0046872
44	0.07	0.646	3.52	0.11	0.82	3hp7A	GO:0003723 GO:0008168 GO:0032259
45	0.07	0.734	3.16	0.15	0.90	4rv9A	GO:0008168 GO:0016740 GO:0032259 GO:0046872 GO:0051536 GO:0051539
46	0.07	0.672	3.62	0.14	0.85	4y2hB	GO:0000122 GO:0003682 GO:0005634 GO:0005654 GO:0005829 GO:0006281 GO:0006284 GO:0006351 GO:0006355 GO:0006479 GO:0006974 GO:0008168 GO:0008469 GO:0016032 GO:0016049 GO:0016274 GO:0016568 GO:0016571 GO:0016740 GO:0019919 GO:0032259 GO:0034970 GO:0035241 GO:0035242 GO:0042054 GO:0042393 GO:0043985 GO:0044020 GO:0045892 GO:0070611 GO:0070612 GO:0090398

Consensus prediction of GO terms

Molecular Function	GO:0051539	GO:0046872	GO:0008757
GO-Score	0.73	0.73	0.41
Biological Processes	GO:0032259
GO-Score	0.84
Cellular Component	GO:0005737
GO-Score	0.41

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv0329c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]