Threading Zmax Znorm MUSTER 5.25 0.91 dPPAS 8.01 0.86 wdPPAS 7.03 0.76 wMUSTER 5.95 1.03 wPPAS 7.95 1.14 dPPAS2 12.84 1.22 PPAS 8.24 1.18 Env-PPAS 5.40 0.67 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=19554) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -1.58 0.52+-0.15 9.5+-4.6 9996 0.212 model2 -4.68 949 0.010 model3 -3.88 877 0.021 model4 -5.00 602 0.007 model5 -5.00 419 0.005 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).