I-TASSER results

I-TASSER results for job id Rv0295c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (267 residues)
MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDD
TILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRS
GDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGA
IAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPM
LERQANQRSDEWVDRYRAEAPRLGLPT

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT
Prediction	CCCCCCCEEEEHCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEHCCHHHHHHHHHHHHHHCCEHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
Conf.Score	999998589997799996899999986776678755545566666545567777646764677777765556555554899999999976777774677763666678888776568876655788999986789789999958857889999999876754557887655666799999999999999999999999999799769987478888599999999999999976567776544578886999999999999878899
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 260 \| \| \| \| \| \| \| \| \| \| \| \| \| MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT
Prediction	856424100000021000100130043333203042104324544335424523452536412420441455335363244015302744444310000000230143025104304524354123203421374010000116230420001020332431434664664442413163025004303522530351056471510302043015303500430052062436336644144137542651164045116656358
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCEEEEHCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEHCCHHHHHHHHHHHHHHCCEHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT

1texD

0.71

0.66

0.93

2.09

MUSTER

--DHPTAYLVLASQRSGSTLLVESLRATGVAGEPQEFFQYLPNTSMSPQPREWFADVEDQSILRLLDPLIEGKPDLAPATIWRDYIQTVGRTPNGVWGGKLMWNQTPLLVQRAKDLPDRSGSGLLSAIRDVVGSDPVLIHIHRPDVVSQAVSFWRAVQTRVWRGAE---------YHAGAIAHVITMLRAQEEGWRAWFTEENVEPIDVDYPYLWRNLTEVVGTVLEALGQDPRLA---------PKPSDEWVERYRRDAQRDGLPL

1texD

0.72

0.66

0.93

2.41

dPPAS

--DHPTAYLVLASQRSGSTLLVESLRATGVAGEPQEFFQYLPNTSMSPQPREWFADVEDQSILRLLDPLIEGKPDLAPATIWRDYIQTVGRTPNGVWGGKLMWNQTPLLVQRAKDLPDRSGSGLLSAIRDVVGSDPVLIHIHRPDVVSQAVSFWRAVQTRVWRG---------AEYHAGAIAHVITMLRAQEEGWRAWFTEENVEPIDVDYPYLWRNLTEVVGTVLEALGQDPRLAP---------KPSDEWVERYRRDAQRDGLPL

1texD

0.71

0.66

0.93

4.11

wdPPAS

--DHPTAYLVLASQRSGSTLLVESLRATGVAGEPQEFFQYLPNTSMSPQPREWFADVEDQSILRLLDPLIEGKPDLAPATIWRDYIQTVGRTPNGVWGGKLMWNQTPLLVQRAKDLPDRSGSGLLSAIRDVVGSDPVLIHIHRPDVVSQAVSFWRAVQTRVWRG---------AEYHAGAIAHVITMLRAQEEGWRAWFTEENVEPIDVDYPYLWRNLTEVVGTVLEALGQDPRLA---------PKPSDEWVERYRRDAQRDGLPL

1texD

0.72

0.66

0.92

2.57

wMUSTER

---HPTAYLVLASQRSGSTLLVESLRATGVAGEPQEFFQYLPNTSMSPQPREWFADVEDQSILRLLDPLIEGKPDLAPATIWRDYIQTVGRTPNGVWGGKLMWNQTPLLVQRAKDLPDRSGSGLLSAIRDVVGSDPVLIHIHRPDVVSQAVSFWRAVQTRVWRG---------AEYHAGAIAHVITMLRAQEEGWRAWFTEENVEPIDVDYPYLWRNLTEVVGTVLEALGQDPRLA---------PKPSDEWVERYRRDAQRDGLPL

1texD

0.71

0.66

0.93

4.71

wPPAS

--DHPTAYLVLASQRSGSTLLVESLRATGVAGEPQEFFQYLPNTSMSPQPREWFADVEDQSILRLLDPLIEGKPDLAPATIWRDYIQTVGRTPNGVWGGKLMWNQTPLLVQRAKDLPDRSGSGLLSAIRDVVGSDPVLIHIHRPDVVSQAVSFWRAVQTRVWRG---------AEYHAGAIAHVITMLRAQEEGWRAWFTEENVEPIDVDYPYLWRNLTEVVGTVLEALGQDPRLA---------PKPSDEWVERYRRDAQRDGLPL

1texD

0.72

0.66

0.93

7.30

dPPAS2

--DHPTAYLVLASQRSGSTLLVESLRATGVAGEPQEFFQYLPNTSMSPQPREWFADVEDQSILRLLDPLIEGKPDLAPATIWRDYIQTVGRTPNGVWGGKLMWNQTPLLVQRAKDLPDRSGSGLLSAIRDVVGSDPVLIHIHRPDVVSQAVSFWRAVQTRVWRG---------AEYHAGAIAHVITMLRAQEEGWRAWFTEENVEPIDVDYPYLWRNLTEVVGTVLEALGQDPRLAP---------KPSDEWVERYRRDAQRDGLPL

1texD

0.71

0.66

0.93

3.56

PPAS

--DHPTAYLVLASQRSGSTLLVESLRATGVAGEPQEFFQYLPNTSMSPQPREWFADVEDQSILRLLDPLIEGKPDLAPATIWRDYIQTVGRTPNGVWGGKLMWNQTPLLVQRAKDLPDRSGSGLLSAIRDVVGSDPVLIHIHRPDVVSQAVSFWRAVQTRVWRG---------AEYHAGAIAHVITMLRAQEEGWRAWFTEENVEPIDVDYPYLWRNLTEVVGTVLEALGQDPRLA---------PKPSDEWVERYRRDAQRDGLPL

1texD

0.71

0.66

0.93

4.79

Env-PPAS

--DHPTAYLVLASQRSGSTLLVESLRATGVAGEPQEFFQYLPNTSMSPQPREWFADVEDQSILRLLDPLIEGKPDLAPATIWRDYIQTVGRTPNGVWGGKLMWNQTPLLVQRAKDLPDRSGSGLLSAIRDVVGSDPVLIHIHRPDVVSQAVSFWRAVQTRVWRG---------AEYHAGAIAHVITMLRAQEEGWRAWFTEENVEPIDVDYPYLWRNLTEVVGTVLEALGQDPRLA---------PKPSDEWVERYRRDAQRDGLPL

4gbmA

0.12

0.11

0.92

1.41

MUSTER

-SRLPGIIFILSSPRSGSTLLRVMLAGHSSLFSPPEL-HLLPFNTMKERQEQLNLSYLGEGLQKTFMEVKN--LDATASQALIKDLESQNLSIQQV------YGMLQENIAPRLLVDKSPTEPTILERGEALFANSKYIYLVR-HPYSVIESFVRMRMQKLVGLGEEN--------PYRVAEQVWAKSNQNILNFLSQLEPE--RQHQIRYEDLVKKPQQVLSQLCDFLNVPFEPELLQPYQRMTGGVHAASLSISDPNFLKHNTID

4gbmA

0.12

0.11

0.93

1.51

dPPAS

-SRLPGIIFILSSPRSGSTLLRVMLAGHSSLFSPPE---LHLLPFNTMKERQEQLNLSYLGEGLQKTFMEVKNLDATASQALIKDLESQNLSIQQVYGM---LQENIAPRLLVDKSPTYAMEPTILERGEALFANSKYIYLVR-HPYSVIESFVRMR--------MQKLVGLGEENPYRVAEQVWAKSNQNILNFLSQLEPE--RQHQIRYEDLVKKPQQVLSQLCDFLNVPFEPEQPYQGDRMTGGVHAASLSISDPNFLKHNTID

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=1.14

Estimated TM-score = 0.87±0.07

Estimated RMSD = 3.6±2.5Å

Download Model 2

C-score=-3.47

Download Model 3

C-score=-3.59

Download Model 4

C-score=-3.78

Download Model 5

C-score=-4.39

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	1texD	0.905	0.97	0.700	0.925
2	2z6vA	0.608	4.36	0.107	0.801
3	4gbmA	0.592	4.03	0.103	0.757
4	4goxA	0.589	3.57	0.143	0.738
5	1zrhA	0.582	4.10	0.077	0.760
6	3ap1A	0.579	3.81	0.135	0.738
7	1nstA	0.577	3.87	0.099	0.738
8	2zq5A	0.576	4.09	0.158	0.757
9	1fmjA	0.576	4.39	0.119	0.771
10	3rnlA	0.575	3.92	0.100	0.734

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.50	12	1texB	TRE	Rep, Mult	14,36,39,48,53,105,163,164
2	0.21	9	3mgcA	PME	Rep, Mult	15,17,19,20,143,152,211
3	0.02	1	3mg9A	UUU	Rep, Mult	21,22,24,25,28,29
4	0.02	1	2zvqX	1NP	Rep, Mult	142,143,144,188,210,212
5	0.02	1	1texA	TRE	Rep, Mult	33,93

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.094	1lvgA	0.480	3.59	0.105	0.596	2.7.4.8	NA
2	0.066	1kofA	0.461	3.94	0.102	0.599	2.7.1.12	17,37
3	0.066	1tevA	0.493	3.85	0.053	0.637	2.7.4.14	100
4	0.066	1khtB	0.478	4.12	0.076	0.622	2.7.4.3	17,19
5	0.066	3hjnA	0.471	4.07	0.060	0.607	2.7.4.9	41
6	0.066	2cdnA	0.470	4.09	0.058	0.618	2.7.4.3	155
7	0.066	1rkbA	0.458	4.21	0.113	0.607	2.7.4.3	17,19
8	0.066	2p0eA	0.473	3.76	0.076	0.599	2.7.1.22	17,19
9	0.066	1qf9A	0.488	4.32	0.065	0.667	2.7.4.14	232
10	0.066	3cm0A	0.467	4.01	0.066	0.614	2.7.4.3	189,196
11	0.066	1z83A	0.486	4.11	0.072	0.640	2.7.4.3	NA
12	0.066	1z6gA	0.489	3.43	0.080	0.603	2.7.4.8	17,209
13	0.066	1ukyA	0.488	4.12	0.067	0.640	2.7.4.-	NA
14	0.060	1q44A	0.523	3.91	0.086	0.682	2.8.2.-	NA
15	0.060	3tmkA	0.494	4.62	0.073	0.667	2.7.4.9	NA
16	0.060	2ccgA	0.497	4.02	0.050	0.644	2.7.4.9	NA
17	0.060	1s3gA	0.492	4.70	0.047	0.693	2.7.4.3	NA
18	0.060	1t8uB	0.572	4.05	0.127	0.749	2.8.2.30	17,145
19	0.060	3cklB	0.571	3.96	0.085	0.730	2.8.2.-	NA
20	0.060	1aqyA	0.560	3.97	0.106	0.727	2.8.2.4	NA
21	0.060	1g3mA	0.564	3.94	0.106	0.727	2.8.2.4	NA
22	0.060	3bd9A	0.568	4.18	0.086	0.753	2.8.2.23	143
23	0.060	2a2zB	0.504	4.38	0.064	0.670	2.7.1.74	36
24	0.060	1zinA	0.503	4.55	0.082	0.704	2.7.4.3	155
25	0.060	1p60A	0.513	4.34	0.057	0.682	2.7.1.74	36
26	0.060	2gwhB	0.566	3.91	0.101	0.727	2.8.2.-	NA
27	0.060	2h8kA	0.500	3.51	0.123	0.625	2.8.2.2	NA
28	0.060	1jagA	0.506	4.29	0.085	0.667	2.7.1.113	NA
29	0.060	3dkvA	0.497	4.42	0.073	0.685	2.7.4.3	196
30	0.060	2bwjA	0.494	3.77	0.080	0.629	2.7.4.3	17,23,36
31	0.060	2qajB	0.496	4.53	0.078	0.689	2.7.4.3	17,23
32	0.060	1j99A	0.544	3.93	0.093	0.700	2.8.2.14,2.8.2.2	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.60	0.905	0.97	0.70	0.93	1texD	GO:0016740
1	0.22	0.589	3.57	0.14	0.74	4goxA	GO:0003824 GO:0008152 GO:0016740 GO:0031177
2	0.21	0.592	4.03	0.10	0.76	4gbmA	GO:0003824 GO:0008152 GO:0016740 GO:0031177 GO:0046872
3	0.17	0.576	4.09	0.16	0.76	2zq5A
4	0.16	0.541	3.85	0.10	0.69	3nibA	GO:0008146
5	0.15	0.561	3.52	0.11	0.70	1q20A	GO:0000103 GO:0004027 GO:0005634 GO:0005737 GO:0005783 GO:0005829 GO:0006629 GO:0008146 GO:0008202 GO:0016740 GO:0043231 GO:0050294 GO:0050427 GO:0070062
6	0.12	0.551	3.88	0.08	0.70	1efhB	GO:0004062 GO:0004304 GO:0005737 GO:0005829 GO:0006629 GO:0007586 GO:0008146 GO:0008202 GO:0016042 GO:0016740 GO:0030573 GO:0047704 GO:0050294 GO:0050427 GO:0051923
7	0.12	0.541	3.90	0.09	0.70	4eecA	GO:0008146 GO:0016740 GO:0017000
8	0.09	0.544	3.93	0.09	0.70	1j99A	GO:0004062 GO:0004304 GO:0005737 GO:0005829 GO:0006629 GO:0007586 GO:0008146 GO:0008202 GO:0016042 GO:0016740 GO:0030573 GO:0047704 GO:0050294 GO:0050427 GO:0051923
9	0.07	0.593	4.19	0.09	0.77	3rnlA	GO:0016740 GO:0046872
10	0.07	0.608	4.36	0.11	0.80	2z6vA
11	0.07	0.579	3.80	0.14	0.74	3ap2A	GO:0000139 GO:0005783 GO:0005794 GO:0006478 GO:0008476 GO:0016020 GO:0016021 GO:0016740 GO:0070062
12	0.07	0.572	3.79	0.11	0.72	2zytX	GO:0000103 GO:0004062 GO:0005737 GO:0006584 GO:0006629 GO:0008146 GO:0016740 GO:0051923
13	0.07	0.573	4.46	0.12	0.77	1x8kA	GO:0008146 GO:0046872
14	0.07	0.567	3.55	0.12	0.71	3bfxA	GO:0004062 GO:0005737 GO:0005829 GO:0008146 GO:0009308 GO:0016740 GO:0050427 GO:0051923 GO:0070062
15	0.07	0.566	3.91	0.10	0.73	2gwhB	GO:0004062 GO:0005737 GO:0005829 GO:0008146 GO:0016740 GO:0050427 GO:0051923
16	0.07	0.539	3.80	0.10	0.69	2ad1A	GO:0004062 GO:0005737 GO:0005829 GO:0008146 GO:0016740 GO:0050427 GO:0051923
17	0.07	0.527	3.89	0.11	0.68	1zd1A	GO:0004062 GO:0005737 GO:0005829 GO:0006629 GO:0006790 GO:0008146 GO:0008202 GO:0016740 GO:0050427
18	0.07	0.500	3.51	0.12	0.63	2h8kA	GO:0004027 GO:0004062 GO:0005737 GO:0006790 GO:0008146 GO:0016740

Consensus prediction of GO terms

Molecular Function	GO:0043169	GO:0031177	GO:0016782
GO-Score	0.42	0.38	0.32
Biological Processes	GO:0008152
GO-Score	0.38
Cellular Component
GO-Score

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.