Threading Zmax Znorm MUSTER 4.29 0.74 dPPAS 7.92 0.85 wdPPAS 5.87 0.63 wMUSTER 4.67 0.80 wPPAS 5.41 0.77 dPPAS2 16.86 1.61 PPAS 6.08 0.87 Env-PPAS 6.03 0.75 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=20200) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -2.55 0.42+-0.14 12.3+-4.4 7665 0.089 model2 -4.15 1844 0.018 model3 -4.52 1199 0.012 model4 -4.73 756 0.010 model5 -4.00 722 0.021 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).