I-TASSER results

Input Sequence in FASTA format

>protein (206 residues)
MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVR
QWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFA
QYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQ
PDDQACIQTLANIYYRAIYSKEDSSN

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQACIQTLANIYYRAIYSKEDSSN
Prediction	CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
Conf.Score	99987589999999999999999999896668999999998998888888789999999999999999999999998557999999999999999999998689999999998689999999999999999999999999999899998999999999999999999999848888888899999999999999998568899999
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQACIQTLANIYYRAIYSKEDSSN
Prediction	85756564355235302500350246430450304230530610330233235423330220032014302530352266744224202300320031036343102001201433540252044015301510240043027444147330420030012101210111023454544423143003000402120021447878
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQACIQTLANIYYRAIYSKEDSSN

3himB

0.17

0.16

0.93

2.16

MUSTER

LGTS------KAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSSPEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFDIEAAALAITSLGIDVSRWF-----PSHTYSDPRIIAARYVELALRMVGCAD----

3himB

0.17

0.16

0.93

1.91

dPPAS

LGTS------KAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSSPEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFDIEAAALAITSLGIDVSRWF-----PSHTYSDPRIIAARYVELALRMVGCAD----

3himB

0.17

0.16

0.93

2.36

wdPPAS

LGTS------KAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSSPEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFDIEAAALAITSLGIDVSRWF-----PSHTYSDPRIIAARYVELALRMVGCAD----

3himB

0.17

0.16

0.93

2.58

wMUSTER

------LGTSKAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSSPEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFDIEAAALAITSLGIDVSRWF-----PSHTYSDPRIIAARYVELALRMVGCAD----

3himB

0.17

0.16

0.93

2.65

wPPAS

LGT------SKAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSSPEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFDIEAAALAITSLGIDVSRWF-----PSHTYSDPRIIAARYVELALRMVGCAD----

3himB

0.17

0.16

0.93

2.52

dPPAS2

LGTS------KAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSSPEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFDIEAAALAITSLGIDVSRWF-----PSHTYSDPRIIAARYVELALRMVGCAD----

2f07A

0.14

0.95

2.46

PPAS

-PFTMPKQTSGKYEKILQAAIEVISEKGLDKASISDIVKKAGTAQGTFYLYFSSKNALIPAIAENLLTHTLDQIKGRLHGDEDFWTVLDILIDETFLITERHKDIIVLCYSGLAI-DHSMEKWETIYQPYYSWLEKIINKAIANHEVTEINSKWTARTIINLVENTAERFYIGFEQ---DENVEVYKKEIFTFLKRSLGTA-----

4w97A

0.19

0.18

0.93

3.06

Env-PPAS

VAGQV----NSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRSQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPLDVDLVYRFIRDTTWVSVRWY-----RPGGPLTAQQVGQQYLAIVLGGITKE-----

2f07A

0.14

0.95

2.16

MUSTER

-PFTMPKQTSGKYEKILQAAIEVISEKGLDKASISDIVKKAGTAQGTFYLYFSSKNALIPAIAENLLTHTLDQIKGRLHGDEDFWTVLDILIDETFLITERHKDIIVLCYSGLAI-DHSMEKWETIYQPYYSWLEKIINKAIANHEVTEINSKWTARTIINLVENTAERFYIGFEQ---DENVEVYKKEIFTFLKRSLGTA-----

2f07A

0.14

0.95

1.89

dPPAS

-PFTMPKQTSGKYEKILQAAIEVISEKGLDKASISDIVKKAGTAQGTFYLYFSSKNALIPAIAENLLTHTLDQIKGRLHGDEDFWTVLDILIDETFLITERHKDIIVLCYSGLAI-DHSMEKWETIYQPYYSWLEKIINKAIANHEVTEINSKWTARTIINLVENTAERFYIGFEQ---DENVEVYKKEIFTFLKRSLGTA-----

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.46

Estimated TM-score = 0.77±0.10

Estimated RMSD = 4.5±3.0Å

Download Model 2

C-score=-1.52

Download Model 3

C-score=-2.47

Download Model 4

C-score=-5.00

Download Model 5

C-score=-4.32

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	3himB	0.879	1.34	0.162	0.927
2	3vprA	0.794	2.21	0.158	0.874
3	3e7qB	0.781	2.75	0.134	0.927
4	4w97A	0.775	2.79	0.197	0.917
5	3bcgA	0.772	2.75	0.122	0.932
6	1t33A	0.768	3.06	0.176	0.947
7	1pb6A	0.760	2.83	0.152	0.927
8	5d1rA	0.754	3.16	0.085	0.947
9	2uxuA	0.751	2.87	0.132	0.927
10	4udsA	0.750	2.33	0.140	0.854

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.10	23	3q0uA	LL3	Rep, Mult	77,87,88,91,92,95,99,123,127,130,133,134,137,160,163,164,167,168,194
2	0.09	22	3br0A	MGR	Rep, Mult	99,102,109,127,130,131,157,160,165
3	0.09	22	3q3sA	O8B	Rep, Mult	74,88,91,92,95,99,106,110,123,127,130,133,134,160,163,164,167,168,194
4	0.07	18	1jumA	BER	Rep, Mult	66,67,70,98,102,127,130,161
5	0.06	10	1jt0A	QNA	Rep, Mult	33,34,45,49,54,55
6	0.04	9	3angD	DCC	Rep, Mult	165,169,173,174,176,177
7	0.04	9	1jt0D	QNA	Rep, Mult	11,12,42,43,44,45,46,47,50,51
8	0.04	9	1vi0A	DCC	Rep, Mult	63,66,67,95,98,109,113,120,124,127,128,131,153,154,156,157,160
9	0.02	5	3aqtB	RCO	Rep, Mult	74,88,91,92,95,133,134,137,160
10	0.02	4	1qvuA	ET	Rep, Mult	103,107,110,114,127,130,161
11	0.02	4	3btjB	DEQ	Rep, Mult	106,109,168,169
12	0.01	3	2i10B	NPO	Rep, Mult	127,128,157
13	0.01	2	3lsrA	QNA	Rep, Mult	33,34,35,39,45,46,49
14	0.01	2	2np5C	NDS	Rep, Mult	113,114,116,120
15	0.01	2	2qop0	III	Rep, Mult	27,28,120,123,124,154,157,158,160,161,162,165,166,168,169,172,173,177,185,188,189,191,193,196,197,200
16	0.00	1	3qbmA	MG	Rep, Mult	115
17	0.00	1	3lsjA	COA	Rep, Mult	87,91,139,194,195,198
18	0.00	1	1jt00	III	Rep, Mult	158,161,162,164,165,166,168,169,170,186,189,190,193,194,196
19	0.00	1	3lsjA	COA	Rep, Mult	82,87,143,195,196,199
20	0.00	1	3angB	DCC	Rep, Mult	169,173,177,182,185,189

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	2qllA	0.453	5.47	0.060	0.743	2.4.1.1	87
2	0.060	2ze0A	0.457	4.60	0.057	0.680	3.2.1.20	NA
3	0.060	1zd3A	0.413	5.09	0.038	0.655	3.3.2.10	131
4	0.060	2qtcB	0.458	5.62	0.053	0.762	1.2.4.1	NA
5	0.060	1o58A	0.434	4.96	0.062	0.704	2.5.1.47	54
6	0.060	2g25A	0.459	5.61	0.080	0.767	1.2.4.1	NA
7	0.060	1tiwA	0.357	5.07	0.031	0.548	1.5.1.12,1.5.99.8	93,190
8	0.060	2r72A	0.463	5.35	0.028	0.777	2.7.7.48	NA
9	0.060	2i2xA	0.436	5.17	0.069	0.714	2.1.1.90	28
10	0.060	3i39X	0.467	5.10	0.044	0.743	1.2.99.2	NA
11	0.060	1vj5A	0.428	5.04	0.057	0.675	3.3.2.10,3.3.2.3	NA
12	0.060	2x38A	0.436	4.97	0.070	0.675	2.7.1.153	36
13	0.060	3c46B	0.377	6.21	0.063	0.723	2.7.7.6	191
14	0.060	1e1yA	0.453	5.49	0.049	0.748	2.4.1.1	87
15	0.060	1m54A	0.437	4.94	0.069	0.704	4.2.1.22	NA
16	0.060	1uyrA	0.453	4.87	0.061	0.699	6.4.1.2,6.3.4.14	NA
17	0.060	1m7xB	0.449	5.22	0.041	0.714	2.4.1.18	NA
18	0.060	1l8aA	0.461	5.66	0.080	0.772	1.2.4.1	NA
19	0.060	3g0bB	0.435	5.37	0.049	0.733	3.4.14.5	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.40	0.719	3.06	0.12	0.89	1jt0A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0045892
1	0.36	0.815	2.25	0.15	0.90	3vprA	GO:0003677 GO:0006351 GO:0006355 GO:0042802
2	0.35	0.735	2.66	0.13	0.88	2np5A	GO:0003677 GO:0006351 GO:0006355
3	0.34	0.648	4.08	0.14	0.93	1rktA	GO:0003677 GO:0006351 GO:0006355
4	0.33	0.701	3.23	0.16	0.90	3ppbA	GO:0003677 GO:0006351 GO:0006355
5	0.32	0.648	3.00	0.10	0.82	4aciB	GO:0000287 GO:0003677 GO:0006351 GO:0006355 GO:0046872
6	0.31	0.879	1.34	0.16	0.93	3himB	GO:0003677 GO:0006351 GO:0006355
7	0.30	0.721	3.15	0.13	0.92	3vibC	GO:0003677 GO:0006351 GO:0006355
8	0.30	0.735	2.91	0.14	0.91	2wuiA	GO:0003677 GO:0006351 GO:0006355
9	0.30	0.712	2.78	0.13	0.85	2iaiA	GO:0003677 GO:0006351 GO:0006355
10	0.29	0.732	3.09	0.14	0.91	3lwjA	GO:0003677 GO:0006351 GO:0006355
11	0.28	0.772	2.75	0.12	0.93	3bcgA	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0008144 GO:0042493 GO:0043565 GO:0045892
12	0.28	0.708	2.78	0.13	0.87	2zcnD	GO:0003677 GO:0006351 GO:0006355
13	0.28	0.599	3.74	0.11	0.83	2np3B	GO:0003677 GO:0006351 GO:0006355
14	0.28	0.680	3.51	0.10	0.89	2hytA	GO:0003677 GO:0006351 GO:0006355
15	0.28	0.782	2.75	0.12	0.93	3lhqA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
16	0.28	0.747	2.75	0.17	0.91	4pxiB	GO:0003677 GO:0006351 GO:0006355
17	0.28	0.708	2.97	0.13	0.89	3geuA	GO:0003677 GO:0006351 GO:0006355
18	0.27	0.775	2.79	0.20	0.92	4w97A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0010468 GO:0019217
19	0.26	0.766	2.73	0.13	0.89	3ccyA	GO:0003677 GO:0006351 GO:0006355
20	0.26	0.697	3.38	0.15	0.91	4me9A	GO:0003677 GO:0006351 GO:0006355
21	0.26	0.741	2.70	0.16	0.90	2genA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
22	0.26	0.763	2.39	0.18	0.88	3f1bA	GO:0003677 GO:0006351 GO:0006355
23	0.25	0.755	2.78	0.18	0.91	3whcA	GO:0003677 GO:0005737 GO:0006351 GO:0006355 GO:0006629 GO:0006631 GO:0016042
24	0.25	0.672	3.83	0.10	0.90	3angC	GO:0003677 GO:0006351 GO:0006355
25	0.24	0.734	3.23	0.14	0.92	3s5rA	GO:0003677 GO:0006351 GO:0006355
26	0.24	0.724	2.86	0.12	0.89	3dewA	GO:0003677 GO:0006351 GO:0006355 GO:0016020 GO:0016021
27	0.24	0.761	3.08	0.13	0.91	4mxmA	GO:0003677 GO:0006351 GO:0006355
28	0.24	0.614	4.02	0.12	0.83	3b81A	GO:0003677 GO:0006351 GO:0006355
29	0.23	0.748	2.91	0.13	0.93	2uxhA	GO:0003677 GO:0006351 GO:0006355
30	0.23	0.730	2.95	0.09	0.90	3nnrA	GO:0003677 GO:0006351 GO:0006355
31	0.23	0.715	2.31	0.12	0.83	2eh3A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0046872
32	0.23	0.617	3.51	0.12	0.81	3ni7A	GO:0003677 GO:0006351 GO:0006355
33	0.22	0.682	3.34	0.18	0.87	3cdlB	GO:0003677 GO:0006351 GO:0006355
34	0.22	0.710	3.16	0.17	0.89	2ibdA	GO:0003677 GO:0006351 GO:0006355
35	0.22	0.729	3.45	0.11	0.94	2id6A	GO:0003677 GO:0006351 GO:0006355
36	0.22	0.690	3.15	0.14	0.87	3dcfA	GO:0003677 GO:0006351 GO:0006355
37	0.22	0.724	3.23	0.14	0.93	3qbmA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
38	0.21	0.588	4.02	0.09	0.81	3bniA	GO:0003677 GO:0006351 GO:0006355
39	0.21	0.696	3.50	0.10	0.91	3rh2A	GO:0003677 GO:0006351 GO:0006355
40	0.21	0.631	3.91	0.08	0.86	3zqgA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
41	0.20	0.632	3.74	0.11	0.84	3cjdA	GO:0003677 GO:0006351 GO:0006355
42	0.20	0.674	3.21	0.12	0.86	5dy0A	GO:0003677 GO:0006351 GO:0006355
43	0.20	0.595	3.91	0.08	0.82	3zqfA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
44	0.19	0.703	2.98	0.10	0.86	3on4A	GO:0003677 GO:0006351 GO:0006355
45	0.19	0.673	3.67	0.08	0.89	5d18A	GO:0003677 GO:0006351 GO:0006355
46	0.19	0.628	3.86	0.15	0.87	2rasB	GO:0003677 GO:0006351 GO:0006355
47	0.19	0.653	3.77	0.12	0.89	3f0cA	GO:0003677 GO:0006351 GO:0006355
48	0.19	0.689	3.33	0.15	0.89	4l62A	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355
49	0.18	0.616	3.99	0.09	0.84	4auxA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
50	0.18	0.676	3.52	0.12	0.89	3mvpA	GO:0003677 GO:0006351 GO:0006355
51	0.17	0.566	4.45	0.07	0.82	2hxiB	GO:0003677 GO:0006351 GO:0006355 GO:0045892
52	0.16	0.567	3.87	0.12	0.79	2qwtA	GO:0003677 GO:0006351 GO:0006355
53	0.16	0.560	4.35	0.06	0.82	2of7A	GO:0003677 GO:0006351 GO:0006355
54	0.16	0.651	3.81	0.10	0.90	3gziA	GO:0003677 GO:0006351 GO:0006355
55	0.16	0.576	3.79	0.10	0.78	4hkuA	GO:0003677 GO:0006351 GO:0006355
56	0.15	0.623	3.95	0.11	0.86	2jj7B	GO:0003677 GO:0006351 GO:0006355 GO:0042802
57	0.15	0.752	3.07	0.12	0.94	3p9tA	GO:0003677 GO:0006351 GO:0006355
58	0.15	0.659	3.85	0.11	0.91	3hggA	GO:0003677 GO:0006351 GO:0006355
59	0.15	0.678	3.71	0.15	0.92	3bhqA	GO:0003677 GO:0006351 GO:0006355
60	0.14	0.737	2.77	0.13	0.90	2hyjA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
61	0.13	0.712	3.36	0.09	0.91	3eupA	GO:0003677 GO:0006351 GO:0006355
62	0.10	0.665	3.58	0.13	0.89	3dpjA	GO:0003677 GO:0006351 GO:0006355
63	0.10	0.672	3.58	0.12	0.90	2fbqA	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355 GO:0044212 GO:0045893 GO:0050714
64	0.10	0.652	3.79	0.10	0.89	2zcxA	GO:0003677 GO:0006351 GO:0006355
65	0.07	0.593	3.99	0.08	0.82	2raeA	GO:0003677 GO:0006351 GO:0006355

Consensus prediction of GO terms

Molecular Function	GO:0003677	GO:0003700	GO:0042802
GO-Score	0.89	0.40	0.36
Biological Processes	GO:0045892
GO-Score	0.40
Cellular Component
GO-Score

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv0273c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]