I-TASSER results

I-TASSER results for job id Rv0259c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Input Sequence in FASTA format

>protein (247 residues)
MNLILTAHGTRRPSGVAMIADIAAQVSALVDRTVQVAFVDVLGPSPSEVLSALSCRPAIV
VPAFLSRGYHVRTDLPAHVAASAHPHVTVTPALGPCREIAQIVTQQLVESGWRPGDSVIL
AAAGASDRRARADLHTTRTLVSELTGSWVDMGFAGTGGPDVRTAVQRARDRAEANRGARR
VAVASFLLAEGLFQERLRASGADVVTRPLGTHPGLAQLVANRFRSAVARQQRLHRWHGTP
TPVTLDL

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MNLILTAHGTRRPSGVAMIADIAAQVSALVDRTVQVAFVDVLGPSPSEVLSALSCRPAIVVPAFLSRGYHVRTDLPAHVAASAHPHVTVTPALGPCREIAQIVTQQLVESGWRPGDSVILAAAGASDRRARADLHTTRTLVSELTGSWVDMGFAGTGGPDVRTAVQRARDRAEANRGARRVAVASFLLAEGLFQERLRASGADVVTRPLGTHPGLAQLVANRFRSAVARQQRLHRWHGTPTPVTLDL
Prediction	CEEEEEHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHCCCCCHHHHHHHHCCCCEEEEHCCCCCCHHHHHHHHHHHHHHCCCCEEEHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
Conf.Score	9699998799998999999999999998589867899875789999999999788868999846678846789999999985899858976789999999999999999767777668999857898568999999999999978986799987578998899999999877887689879999767668845999999999998756798999999999999999984667787888876555579
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 220 240 \| \| \| \| \| \| \| \| \| \| \| \| MNLILTAHGTRRPSGVAMIADIAAQVSALVDRTVQVAFVDVLGPSPSEVLSALSCRPAIVVPAFLSRGYHVRTDLPAHVAASAHPHVTVTPALGPCREIAQIVTQQLVESGWRPGDSVILAAAGASDRRARADLHTTRTLVSELTGSWVDMGFAGTGGPDVRTAVQRARDRAEANRGARRVAVASFLLAEGLFQERLRASGADVVTRPLGTHPGLAQLVANRFRSAVARQQRLHRWHGTPTPVTLDL
Prediction	4000000010236502510340052047227250200001236141440055056440000000002242134202510561632512102022324300300240044243344432210232354441342034004102642423020010123413045004404644446341310000001001320152047204410051023142004001300420265454245444313303267
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CEEEEEHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHCCCCCHHHHHHHHCCCCEEEEHCCCCCCHHHHHHHHHHHHHHCCCCEEEHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
MNLILTAHGTRRPSGVAMIADIAAQVSALVDRTVQVAFVDVLGPSPSEVLSALSCRPAIVVPAFLSRGYHVRTDLPAHVAASAHPHVTVTPALGPCREIAQIVTQQLVESGWRPGDSVILAAAGASDRRARADLHTTRTLVSELTGSWVDMGFAGTGGPDVRTAVQRARDRAEANRGARRVAVASFLLAEGLFQERLRASGADVVTRPLGTHPGLAQLVANRFRSAVARQQRLHRWHGTPTPVTLDL

4ccsA

0.18

0.16

0.85

1.76

MUSTER

RNVLIVAHGQPGAPQQRAIEALAARVAPLPQACVRGATLA-MPGALDRA-----DDETLIYPLFMATGWFTRSELPRRLALAGAPKARILPPFGSDPGLPALCLALIAQAAPLAGTRLLVAAHGSGRRAPSEAARRIAAGLAPYAA-AATCGFIE-EAPFIADAARDL---------PERAICLPLFATQAEHVTDLPAALSQAVLPPVGLAPQVPAMIAESIKAALS-------------------

4ccsA

0.19

0.17

0.86

1.88

dPPAS

RNVLIVAHGQPGAPQQRAIEALAARVAPLPQACVRGATLAMPGAL------DRADDETLIYPLFMATGWFTRSELPRRLALAGAPKARILPPFGSDPGLPALCLALIAQAAPLAGTRLLVAAHGSGRSRAPSEAARRIAAGLAPYAAAATCGFI-EEAPFIADAARD---------LPERAICLPLFATQAEHVTDLPAALSQAVLPPVGLAPQVPAMIAESIKAALS-------------------

4ccsA

0.19

0.17

0.86

2.54

wdPPAS

RNVLIVAHGQPGAPQQRAIEALAARVAPLPQACVRGATLAMPG------ALDRADDETLIYPLFMATGWFTRSELPRRLALAGAPKARILPPFGSDPGLPALCLALIAQAAPLAGTRLLVAAHGSGRSRAPSEAARRIAAGLAPYAAAATCGFIE-EAPFIADAARDL---------PERAICLPLFATQAEHVTDLPAALSQAVLPPVGLAPQVPAMIAESIKAALS-------------------

4ccsA

0.19

0.16

0.85

2.08

wMUSTER

-NVLIVAHGQPGAPQQRAIEALAARVAPLPQACVRGATLA-MPGALDR-----ADDETLIYPLFMATGWFTRSELPRRLALAGAPKARILPPFGSDPGLPALCLALIAQAAPLAGTRLLVAAHGSGRSRAPSEAARRIAAGLAPYAAAATCGFIE-EAPFIADAARDL---------PERAICLPLFATQAEHVTDLPAALSQAVLPPVGLAPQVPAMIAESIKAALS-------------------

4ccsA

0.19

0.16

0.86

3.11

wPPAS

RNVLIVAHGQPGAPQQRAIEALAARVAPLPQACVRGATLAM-PGALDR-----ADDETLIYPLFMATGWFTRSELPRRLALAGAPKARILPPFGSDPGLPALCLALIAQAAPLAGTRLLVAAHGSGRSRAPSEAARRIAAGLAPYAAAATCGFIE-EAPFIADAARDL---------PERAICLPLFATQAEHVTDLPAALSQAVLPPVGLAPQVPAMIAESIKAALS-------------------

4ccsA

0.19

0.17

0.86

4.83

dPPAS2

RNVLIVAHGQPGAPQQRAIEALAARVAPLPQACVRGATLAMPGAL------DRADDETLIYPLFMATGWFTRSELPRRLALAGAPKARILPPFGSDPGLPALCLALIAQAAPLAGTRLLVAAHGSGRSRAPSEAARRIAAGLAPYAAAATCGFIE-EAPFIADAARDL---------PERAICLPLFATQAEHVTDLPAALSQAVLPPVGLAPQVPAMIAESIKAALS-------------------

4ccsA

0.19

0.16

0.86

2.70

PPAS

RNVLIVAHGQPGAPQQRAIEALAARVAPLPQACVRGATLA-MPGALDR-----ADDETLIYPLFMATGWFTRSELPRRLALAGAPKARILPPFGSDPGLPALCLALIAQAAPLAGTRLLVAAHGSGRSRAPSEAARRIAAGLAPYAAAATCGFIE-EAPFIADAARD---------LPERAICLPLFATQAEHVTDLPAALSQAVLPPVGLAPQVPAMIAESIKAALS-------------------

4ccsA

0.19

0.16

0.86

4.03

Env-PPAS

RNVLIVAHGQPGAPQQRAIEALAARVAPLPQACVRGATLA-MPGALDR-----ADDETLIYPLFMATGWFTRSELPRRLALAGAPKARILPPFGSDPGLPALCLALIAQAAPLAGTRLLVAAHGSGRSRAPSEAARRIAAGLAPYAAAATCGFIE-EAPFIADAARDL---------PERAICLPLFATQAEHVTDLPAALSQAVLPPVGLAPQVPAMIAESIKAALS-------------------

2xvxA

0.21

0.19

0.90

1.31

MUSTER

TGILLVAFGTSVEEARPALDKMGDRVRAAPDIPVRWAYTAIAAPSPAEALAGMAETHVAVQSLHTIPG-EEFHGLLETAHAFQGLPVSVGLPLIGTTADAEAVAEALVASDRKPGEPVVFMGHGTPH-PADICYPGLQYYLWRL-DPDLLVGTVE-GSPSFDNVMAELDVRK-----AKRVWLMPLMAVAGDHARNWTSQLARRVLHGTAESDAVAAIWLRHLDDALARLN----------------

2xvxA

0.20

0.18

0.90

1.25

dPPAS

TGILLVAFGTSVEEARPALDKMGDRVRAAPDIPVRWAYTGIAAPSPAEALAGMAFTHVAVQSLHTIPG-EEFHGLLETAHAFQGLPVSVGLPLIGTTADAEAVAEALVASDRKPGEPVVFMGHGTPH-PADICYPGLQYYLWRLDPD--LLVGTVEGSPSFDNVMAELDVRK-----AKRVWLMPLMAVAGDHARNWTSQLARRVLHGTAESDAVAAIWLRHLDDALARLN----------------

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=-0.34

Estimated TM-score = 0.67±0.13

Estimated RMSD = 6.5±3.9Å

Download Model 2

C-score=-1.45

Download Model 3

C-score=-0.65

Download Model 4

C-score=-2.05

Download Model 5

C-score=-1.47

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4ccsA	0.789	1.90	0.193	0.858
2	1hrkA	0.776	3.03	0.093	0.943
3	1lbqA	0.775	2.90	0.085	0.935
4	2ac4A	0.759	2.83	0.124	0.911
5	2xvxA	0.749	2.86	0.180	0.899
6	1qgoA	0.725	3.05	0.160	0.887
7	2jh3A	0.724	3.42	0.214	0.895
8	2c4kA	0.601	4.58	0.122	0.858
9	1dkrB	0.591	4.60	0.077	0.838
10	3dahC	0.589	4.42	0.117	0.826

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.09	5	2xvyA	CO	Rep, Mult	8,40,70
2	0.07	4	2xvzA	HEM	Rep, Mult	67,72,75,91,127,128,130
3	0.07	4	2xwqA	SIR	Rep, Mult	123,124,125,126,156,157,187,188,191,192,193
4	0.05	3	2xwpA	SIR	Rep, Mult	8,40,41,64,65,66,68,70,123,124,125,187,188,189,196
5	0.04	2	2qd1D	PP9	Rep, Mult	21,22,25,209
6	0.04	2	2xvxA	HEM	Rep, Mult	67,73,76,77,80,129
7	0.02	1	2z0aD	GLY	Rep, Mult	225,229
8	0.02	1	2jh3B	SF4	Rep, Mult	103,106,184,208,211,212,215
9	0.02	1	4nxaA	XE	Rep, Mult	93,99,103,209,215
10	0.02	1	4f8eA	MG	Rep, Mult	1,3,227
11	0.02	1	3p52A	NO3	Rep, Mult	5,6,62,219
12	0.02	1	2fkaA	CXS	Rep, Mult	30,220,224
13	0.02	1	3eteD	H3P	Rep, Mult	140,141,143
14	0.02	1	2e85B	CA	Rep, Mult	106,109

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.253	2c8jA	0.763	2.86	0.102	0.915	4.99.1.1	8
2	0.195	1lbqA	0.775	2.90	0.085	0.935	4.99.1.1	8
3	0.193	1qgoA	0.725	3.05	0.160	0.887	4.99.1.3	10,188
4	0.060	1b3bE	0.540	5.18	0.075	0.854	1.4.1.3	98,219
5	0.060	3etdA	0.573	5.03	0.082	0.878	1.4.1.3	NA
6	0.060	3k92A	0.559	5.26	0.040	0.870	1.4.1.2	NA
7	0.060	2j6iA	0.545	5.13	0.064	0.834	1.2.1.2	NA
8	0.060	1u9yC	0.574	3.82	0.123	0.757	2.7.6.1	NA
9	0.060	2fssA	0.548	5.15	0.060	0.834	1.2.1.2	NA
10	0.060	3k2qA	0.544	4.79	0.072	0.802	2.7.1.90	9
11	0.060	1hrkA	0.776	3.03	0.093	0.943	4.99.1.1	NA
12	0.060	3h9uC	0.549	5.25	0.069	0.846	3.3.1.1	NA
13	0.060	3d64B	0.551	4.96	0.071	0.822	3.3.1.1	NA
14	0.060	1bgvA	0.552	5.26	0.093	0.875	1.4.1.2	NA
15	0.060	1dozA	0.761	2.81	0.124	0.911	4.99.1.1	8
16	0.060	1dkrB	0.591	4.60	0.077	0.838	2.7.6.1	NA
17	0.060	1x15A	0.555	4.71	0.098	0.810	1.6.1.2	NA
18	0.060	2f48B	0.548	4.85	0.082	0.822	2.7.1.90	11
19	0.060	1bw9A	0.564	4.72	0.106	0.814	1.4.1.20	NA
20	0.060	1v8bC	0.549	5.26	0.060	0.846	3.3.1.1	209
21	0.060	1hrdA	0.518	5.52	0.076	0.854	1.4.1.2	20
22	0.060	3hnoA	0.549	4.64	0.099	0.798	2.7.1.90	11

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.25	0.775	3.04	0.09	0.94	3aqiA	GO:0004325 GO:0005739 GO:0005743 GO:0005759 GO:0006091 GO:0006779 GO:0006783 GO:0008198 GO:0009416 GO:0010038 GO:0010288 GO:0016020 GO:0016829 GO:0017085 GO:0042493 GO:0045471 GO:0046501 GO:0046685 GO:0046872 GO:0051536 GO:0051537 GO:0051597 GO:0070541 GO:0071549
1	0.22	0.748	2.88	0.18	0.90	2xvzA	GO:0016829 GO:0016852 GO:0019251 GO:0020037 GO:0042597 GO:0046872 GO:0050897 GO:0051262 GO:0051266
2	0.22	0.758	2.86	0.12	0.91	2ac2A	GO:0004325 GO:0005737 GO:0006779 GO:0006783 GO:0016829 GO:0046872
3	0.21	0.725	3.05	0.16	0.89	1qgoA	GO:0006779 GO:0009236 GO:0016829 GO:0016852 GO:0019251 GO:0046872 GO:0046906 GO:0050897
4	0.17	0.388	2.77	0.22	0.45	2dj5A	GO:0009236 GO:0016829 GO:0016852 GO:0019251 GO:0046872 GO:0046906 GO:0050897
5	0.14	0.763	2.86	0.10	0.92	2c8jA	GO:0004325 GO:0005737 GO:0006779 GO:0006783 GO:0016829 GO:0046872
6	0.14	0.775	2.90	0.09	0.94	1lbqA	GO:0004325 GO:0005739 GO:0005743 GO:0006779 GO:0006783 GO:0016020 GO:0016829
7	0.12	0.396	2.46	0.20	0.46	3lyhB	GO:0009236 GO:0016852
8	0.07	0.446	5.34	0.08	0.70	2iv7A	GO:0008919 GO:0009103 GO:0009244 GO:0016740 GO:0016757
9	0.07	0.300	5.69	0.06	0.49	4x6uA	GO:0004806 GO:0016787 GO:0046872
10	0.06	0.408	5.21	0.06	0.62	3ct4A	GO:0004371 GO:0006071 GO:0016301 GO:0016310 GO:0016740 GO:0019563
11	0.06	0.433	4.94	0.06	0.64	1c47A	GO:0000287 GO:0004614 GO:0005737 GO:0005975 GO:0006006 GO:0016529 GO:0016853 GO:0016868 GO:0046872 GO:0071704
12	0.06	0.408	5.32	0.04	0.62	4qlaA	GO:0003824 GO:0005783 GO:0005789 GO:0016020 GO:0016021 GO:0016787 GO:0019439 GO:0031090 GO:0033961 GO:0043231
13	0.06	0.366	5.19	0.04	0.55	3tbfC	GO:0004360 GO:0005737 GO:0005975 GO:0006541 GO:0008483 GO:0016740 GO:0030246 GO:1901137
14	0.06	0.393	6.15	0.06	0.68	2vr2A	GO:0002058 GO:0002059 GO:0004157 GO:0005737 GO:0005829 GO:0006208 GO:0006210 GO:0006212 GO:0008270 GO:0016597 GO:0016787 GO:0016810 GO:0019482 GO:0019860 GO:0046135 GO:0046872 GO:0051219 GO:0051260 GO:0051289 GO:0070062
15	0.06	0.343	5.56	0.04	0.57	4uhmA	GO:0003824 GO:0008483 GO:0016740 GO:0030170
16	0.06	0.363	5.15	0.07	0.55	3gemC	GO:0016491 GO:0055114
17	0.06	0.257	6.06	0.07	0.46	1fpsA	GO:0004161 GO:0004337 GO:0005737 GO:0006629 GO:0006694 GO:0006695 GO:0008202 GO:0008203 GO:0008299 GO:0016126 GO:0016740 GO:0033384 GO:0045337 GO:0046872
18	0.06	0.303	5.85	0.07	0.51	1gynA	GO:0003824 GO:0004332 GO:0005618 GO:0005829 GO:0005886 GO:0005975 GO:0006094 GO:0006096 GO:0008270 GO:0016829 GO:0016832 GO:0046872
19	0.06	0.337	5.11	0.05	0.51	1oquC	GO:0004748 GO:0005971 GO:0006260 GO:0009186 GO:0009263 GO:0016491 GO:0046872 GO:0055114
20	0.06	0.291	5.13	0.06	0.46	4m85A	GO:0008080

Consensus prediction of GO terms

Molecular Function	GO:0051536	GO:0005506	GO:0016852	GO:0050897	GO:0004325	GO:0046906
GO-Score	0.50	0.50	0.50	0.50	0.41	0.35
Biological Processes	GO:1990267	GO:0009314	GO:0010035	GO:0009636	GO:0097305	GO:1901655	GO:0071548	GO:0071385	GO:0019251	GO:0051259	GO:0006783
GO-Score	0.50	0.50	0.50	0.50	0.50	0.50	0.50	0.50	0.50	0.45	0.41
Cellular Component	GO:0031966	GO:0070013	GO:0019866
GO-Score	0.50	0.50	0.50

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.