Threading Zmax Znorm MUSTER 4.32 0.75 dPPAS 8.24 0.89 wdPPAS 8.53 0.92 wMUSTER 4.58 0.79 wPPAS 7.40 1.06 dPPAS2 11.55 1.10 PPAS 7.45 1.06 Env-PPAS 6.01 0.75 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=13539) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.76 0.31+-0.10 14.7+-3.6 2047 0.025 model2 -3.79 1883 0.025 model3 -3.70 1460 0.027 model4 -4.31 1013 0.015 model5 -4.16 1261 0.017 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).