Threading Zmax Znorm MUSTER 5.65 0.97 dPPAS 7.67 0.82 wdPPAS 10.47 1.13 wMUSTER 5.70 0.98 wPPAS 10.08 1.44 dPPAS2 13.79 1.31 PPAS 8.41 1.20 Env-PPAS 8.32 1.04 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=4008) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.58 0.32+-0.11 14.4+-3.7 592 0.025 model2 -4.01 452 0.016 model3 -3.23 378 0.035 model4 -4.16 370 0.014 model5 -2.76 358 0.057 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).