Threading Zmax Znorm MUSTER 5.00 0.86 dPPAS 8.07 0.87 wdPPAS 6.24 0.67 wMUSTER 4.77 0.82 wPPAS 6.87 0.98 dPPAS2 14.37 1.37 PPAS 7.01 1.00 Env-PPAS 5.12 0.64 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=13539) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.71 0.31+-0.10 15.2+-3.4 2128 0.027 model2 -4.45 1007 0.013 model3 -4.05 905 0.019 model4 -4.89 492 0.008 model5 -4.75 454 0.010 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).