I-TASSER results

Input Sequence in FASTA format

>protein (201 residues)
MTAVAAGALVVETDSFRLRLLDGLVASIGERGYRATTVSDIVRHARTSKRTFYDRFTSKE
QCFLELLLADNETLGNSIRAAVDPNADWHDQIRQAVEAYVTHIESRPAVTLSWIREFPSL
GAAAYPVQRRGMEQLTSLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQ
PIRNIVEPAVDASIALLGPRS

Predicted Secondary Structure

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MTAVAAGALVVETDSFRLRLLDGLVASIGERGYRATTVSDIVRHARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRAAVDPNADWHDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLTSLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIVEPAVDASIALLGPRS
Prediction	CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
Conf.Score	999899988887899999999999999999896668899999998998888898789999999999999999999999999858999999999999999999998867899999876658989999999999999999999999985886799877999999999999999999985799988999999999999976689
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 60 80 100 120 140 160 180 200 \| \| \| \| \| \| \| \| \| \| MTAVAAGALVVETDSFRLRLLDGLVASIGERGYRATTVSDIVRHARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRAAVDPNADWHDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLTSLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIVEPAVDASIALLGPRS
Prediction	645556664555465214301500350235431360314440531412322034327323200210043015402520451166754134001200310031025233101000110341456125303411430041024103522364470462203000100310110012013576414501330030012003348
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Normalized B-facotr

(B-factor is a value to indicate the extent of the inherent thermal mobility of residues/atoms in proteins. In I-TASSER, this value is deduced from threading template proteins from the PDB in combination with the sequence profiles derived from sequence databases. The reported B-factor profile in the figure below corresponds to the normalized B-factor of the target protein, defined by B=(B'-u)/s, where B' is the raw B-factor value, u and s are respectively the mean and standard deviation of the raw B-factors along the sequence. (Click here to read more about predicted normalized B-factor)

Top 10 threading templates used by I-TASSER

Rank

PDB
Hit

Iden1

Iden2

Cov

Norm.
Zscore

Download
Align.

                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200

                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |

Sec.Str
Seq

CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
MTAVAAGALVVETDSFRLRLLDGLVASIGERGYRATTVSDIVRHARTSKRTFYDRFTSKEQCFLELLLADNETLGNSIRAAVDPNADWHDQIRQAVEAYVTHIESRPAVTLSWIREFPSLGAAAYPVQRRGMEQLTSLLIELSASPGFRRANLPPLNVPLAVILLGGLRELTALTVEDGQPIRNIVEPAVDASIALLGPRS

3himB

0.18

0.17

0.95

2.17

MUSTER

LGTS----------KAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSLS-PEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFDIEAAALAITSLGIDVSRWFPSHTYPRIIAARYVELALRMVGCAD

4w97A

0.22

0.21

0.96

1.97

dPPAS

-------RVAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPLDVDLVYRFIRDTTWVSVRWYRPGGPAQQVGQQYLAIVLGGITKE-

3himB

0.18

0.17

0.95

2.48

wdPPAS

LGTS----------KAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSLSPEHFAIIADIRRSTTKVFTRIIEAGATAG-DFHPFDIEAAALAITSLGIDVSRWFPSHTDPRIIAARYVELALRMVGCAD

4w97A

0.21

0.20

0.96

2.58

wMUSTER

--------VAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPLDVDLVYRFIRDTTWVSVRWYRPGGTAQQVGQQYLAIVLGGITKE-

3himB

0.18

0.17

0.95

2.80

wPPAS

LGT----------SKAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSLSPEHFAIIADIRRSTTKVFTRIIEAGATAG-DFHPFDIEAAALAITSLGIDVSRWFPSHTYPRIIAARYVELALRMVGCAD

4w97A

0.22

0.21

0.96

2.64

dPPAS2

-------RVAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPLDVDLVYRFIRDTTWVSVRWYRPGGPAQQVGQQYLAIVLGGITKE-

4w97A

0.22

0.21

0.96

2.54

PPAS

-------RVAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPLDVDLVYRFIRDTTWVSVRWYRPGGPAQQVGQQYLAIVLGGITKE-

4w97A

0.22

0.21

0.96

3.40

Env-PPAS

-------RVAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPLDVDLVYRFIRDTTWVSVRWYRPGGPAQQVGQQYLAIVLGGITKE-

4w97A

0.21

0.20

0.96

2.16

MUSTER

-------RVAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPLDVDLVYRFIRDTTWVSVRWYRPGGTAQQVGQQYLAIVLGGITKE-

3himB

0.19

0.18

0.95

1.97

dPPAS

----------LGTSKAAARIRAAAIEVFAAKGYGATTTREIAASLDMSPGAVYPHYKTKESLLYAISLEGHHSVLAAITAADFPDIAAPDRLMSTVTAYVTWHADNRASARVGQYELRSLS-PEHFAIIADIRRSTTKVFTRIIEAGATAGDFHPFDIEAAALAITSLGIDVSRWFPSHTDPRIIAARYVELALRMVGCAD

(a)	Iden1 is the number of template residues identical to query divided by number of aligned residues.
(b)	Iden2 is the number of template residues identical to query divided by query sequence length.
(c)	Cov is equal the number of aligned template residues divided by query sequence length.
(d)	Norm. Zscore is the normalized Z-score of the threading alignments. A Normalized Z-score >1 means a good alignment.
(e)	Download Align. list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.

Top 5 final models predicted by I-TASSER

(For each target, I-TASSER simulations generate a large ensemble of structural conformations, called decoys. To select the final models, I-TASSER uses the SPICKER program to cluster all the decoys based on the pair-wise structure similarity, and reports up to five models which corresponds to the five largest structure clusters. The confidence of each model is quantitatively measured by C-score that is calculated based on the significance of threading template alignments and the convergence parameters of the structure assembly simulations. C-score is typically in the range of [-5, 2], where a C-score of higher value signifies a model with a high confidence and vice-versa. TM-score and RMSD are estimated based on C-score and protein length following the correlation observed between these qualities. Since the top 5 models are ranked by the cluster size, it is possible that the lower-rank models have a higher C-score in rare cases. Although the first model has a better quality in most cases, it is also possible that the lower-rank models have a better quality than the higher-rank models as seen in our benchmark tests. If the I-TASSER simulations converge, it is possible to have less than 5 clusters generated. This is usually an indication that the models have a good quality because of the converged simulations.)

More about C-score

Local structure accuracy of first model

Download Model 1

C-score=0.48

Estimated TM-score = 0.78±0.10

Estimated RMSD = 4.4±2.9Å

Download Model 2

C-score=-0.69

Download Model 3

C-score=-2.98

Download Model 4

C-score=-2.04

Download Model 5

C-score=-5.00

Proteins structureally close to the target in PDB (as identified by TM-align

(After the structure assembly simulation, I-TASSER uses the TM-align structural alignment program to match the first I-TASSER model to all structures in the PDB library. This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e. the highest TM-score, to the predicted I-TASSER model. Due to the structural similarity, these proteins often have similar function to the target. However, users are encouraged to use the data in the next section 'Predicted function using COACH' to infer the function of the target protein, since COACH has been extensively trained to derive biological functions from multi-source of sequence and structure features which has on average a higher accuracy than the function annotations derived only from the global structure comparison.)

Top 10 Identified stuctural analogs in PDB

Rank	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov
1	4w97A	0.884	1.68	0.214	0.955
2	3himB	0.871	1.79	0.189	0.945
3	3vprA	0.819	1.90	0.202	0.895
4	2ibdA	0.777	2.26	0.199	0.895
5	4g12A	0.775	2.51	0.188	0.900
6	3ccyA	0.770	2.37	0.144	0.871
7	4udsA	0.759	2.15	0.125	0.861
8	5e57A	0.758	2.58	0.156	0.895
9	4gctA	0.753	2.56	0.151	0.890
10	3f1bA	0.736	2.59	0.174	0.866

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted function using COACH

(This section reports biological annotations of the target protein by COACH based on the I-TASSER structure prediction. COACH is a meta-server approach that combines multiple function annotation results from the COFACTOR, TM-SITE and S-SITE programs.)

Ligand binding sites

Rank	C-score	Cluster size	PDB Hit	Lig Name	Download Complex	Ligand Binding Site Residues
1	0.14	35	3sfiA	3SF	Rep, Mult	78,81,91,92,95,96,99,103,129,136,139,140,166,169,170,173,193
2	0.09	22	4w97A	UCA	Rep, Mult	70,113,114,133,136,163,166,167,170
3	0.05	8	1jt0A	QNA	Rep, Mult	37,38,49,53,58,59
4	0.05	12	1jumA	BER	Rep, Mult	70,71,74,102,106,133,136,166
5	0.04	11	3q0vA	LL4	Rep, Mult	78,91,92,95,96,99,133,139,140,143,166,169,193
6	0.04	11	3br1A	DEQ	Rep, Mult	67,70,71,74,102,103,106,110,114,129,136
7	0.03	8	3angD	DCC	Rep, Mult	70,99,113,117,118,125,126,129,132,157,160,163,166,167,170
8	0.03	8	1vi0B	DCC	Rep, Mult	171,174,175,179,180
9	0.03	8	2uxiB	G50	Rep, Mult	74,110,129,133,170
10	0.03	7	1jt0D	QNA	Rep, Mult	15,16,46,47,48,49,50,51,54,55
11	0.02	5	3angA	DCC	Rep, Mult	70,113,117,127,128,131,136,157,160,163,167,170
12	0.01	2	3lsrA	NUC	Rep, Mult	8,9,37,38,39,43,49,50,53
13	0.01	2	1jt00	III	Rep, Mult	111,115,163,167,169,170,173,174,175,188,191,192,195,196,198
14	0.01	4	3btjB	DEQ	Rep, Mult	108,111,174,175
15	0.01	2	2nx40	III	Rep, Mult	25,26,27,111,114,117,119,130,137,157,159,160,163,164,167,168,171,174,187,189,192,193
16	0.01	2	3lsjA	COA	Rep, Mult	86,91,149,194,195,198
17	0.00	1	3locB	URA	Rep, Mult	21,24,25,37,59
18	0.00	1	2v57A	PRL	Rep, Mult	71,74,75,78,110,132,141,162,166
19	0.00	1	3locA	URA	Rep, Mult	175
20	0.00	1	3angB	DCC	Rep, Mult	175,180,181,184,188

	Download the all possible binding ligands and detailed prediction summary.
	Download the templates clustering results.
(a)	C-score is the confidence score of the prediction. C-score ranges [0-1], where a higher score indicates a more reliable prediction.
(b)	Cluster size is the total number of templates in a cluster.
(c)	Lig Name is name of possible binding ligand. Click the name to view its information in the BioLiP database.
(d)	Rep is a single complex structure with the most representative ligand in the cluster, i.e., the one listed in the Lig Name column. Mult is the complex structures with all potential binding ligands in the cluster.

Enzyme Commission (EC) numbers and active sites

Rank	Cscore^EC	PDB Hit	TM-score	RMSD^a	IDEN^a	Cov	EC Number	Active Site Residues
1	0.060	3i39X	0.443	5.48	0.072	0.761	1.2.99.2	103,174
2	0.060	2zpuA	0.441	4.92	0.063	0.697	5.1.1.18	NA
3	0.060	1z7wA	0.440	4.84	0.085	0.697	2.5.1.47	NA
4	0.060	1udyA	0.440	4.46	0.086	0.652	1.3.99.3	187
5	0.060	1j0bU	0.448	4.96	0.050	0.721	3.5.99.7	NA
6	0.060	1rqxC	0.448	5.07	0.056	0.736	3.5.99.7	NA
7	0.060	2b0cA	0.350	4.98	0.061	0.577	3.1.3.-	NA
8	0.060	1tdjA	0.440	4.84	0.069	0.692	4.3.1.19	NA
9	0.060	1zd3A	0.452	4.44	0.092	0.677	3.3.2.10	67
10	0.060	1p6xA	0.442	5.11	0.024	0.707	2.7.1.21	NA
11	0.060	1tzmC	0.447	5.05	0.055	0.736	3.5.99.7	19
12	0.060	2z1qB	0.443	5.57	0.083	0.771	1.3.99.3	65
13	0.060	1vj5A	0.471	4.25	0.086	0.692	3.3.2.10,3.3.2.3	NA
14	0.060	2zr8A	0.440	4.84	0.057	0.692	5.1.1.18	NA
15	0.060	1s6yA	0.442	4.77	0.061	0.677	3.2.1.86	NA
16	0.060	2uxwA	0.443	5.26	0.053	0.736	1.3.99.-	23,65
17	0.060	3mddA	0.341	5.10	0.061	0.547	1.3.99.3	NA
18	0.060	1ig8A	0.435	4.66	0.027	0.662	2.7.1.1	43
19	0.060	1xmeA	0.459	4.95	0.090	0.716	1.9.3.1	NA

(a)	Cscore^EC is the confidence score for the EC number prediction. Cscore^EC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Gene Ontology (GO) terms

Rank	Cscore^GO	TM-score	RMSD^a	IDEN^a	Cov	PDB Hit	Associated GO Terms
Homologous GO templates in PDB
0	0.43	0.696	3.32	0.15	0.92	1jt0A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0045892
1	0.43	0.838	1.88	0.20	0.92	3vprA	GO:0003677 GO:0006351 GO:0006355 GO:0042802
2	0.42	0.785	2.53	0.18	0.92	4g12A	GO:0003677 GO:0006351 GO:0006355
3	0.41	0.884	1.68	0.21	0.96	4w97A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0010468 GO:0019217
4	0.37	0.748	2.43	0.13	0.88	2iaiA	GO:0003677 GO:0006351 GO:0006355
5	0.36	0.628	3.43	0.12	0.83	4aciB	GO:0000287 GO:0003677 GO:0006351 GO:0006355 GO:0046872
6	0.36	0.786	2.26	0.20	0.91	2ibdA	GO:0003677 GO:0006351 GO:0006355
7	0.35	0.709	3.22	0.14	0.91	3whcA	GO:0003677 GO:0005737 GO:0006351 GO:0006355 GO:0006629 GO:0006631 GO:0016042
8	0.34	0.658	3.62	0.16	0.90	3ppbA	GO:0003677 GO:0006351 GO:0006355
9	0.33	0.720	3.39	0.14	0.93	3bcgA	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0008144 GO:0042493 GO:0043565 GO:0045892
10	0.33	0.715	3.42	0.17	0.93	3pasB	GO:0003677 GO:0006351 GO:0006355
11	0.33	0.725	3.31	0.15	0.93	2id6A	GO:0003677 GO:0006351 GO:0006355
12	0.32	0.795	2.38	0.14	0.90	3ccyA	GO:0003677 GO:0006351 GO:0006355
13	0.32	0.757	2.63	0.17	0.89	3f1bA	GO:0003677 GO:0006351 GO:0006355
14	0.32	0.871	1.79	0.19	0.95	3himB	GO:0003677 GO:0006351 GO:0006355
15	0.31	0.749	3.17	0.14	0.94	3lhqA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
16	0.30	0.761	3.15	0.14	0.93	4mxmA	GO:0003677 GO:0006351 GO:0006355
17	0.30	0.761	2.56	0.12	0.90	4gclB	GO:0003677 GO:0005737 GO:0007049 GO:0009295 GO:0010974 GO:0043565 GO:0043590 GO:0051301 GO:0051302
18	0.30	0.548	4.18	0.11	0.79	2np3B	GO:0003677 GO:0006351 GO:0006355
19	0.30	0.681	3.66	0.11	0.91	3vibC	GO:0003677 GO:0006351 GO:0006355
20	0.29	0.703	2.96	0.12	0.89	2zcnD	GO:0003677 GO:0006351 GO:0006355
21	0.29	0.728	2.95	0.13	0.89	4ichA	GO:0003677 GO:0006351 GO:0006355
22	0.28	0.776	2.48	0.15	0.91	4gctC	GO:0000976 GO:0003677 GO:0003700 GO:0005737 GO:0005829 GO:0006355 GO:0007049 GO:0009295 GO:0010974 GO:0043565 GO:0043590 GO:0051301 GO:0051302
23	0.28	0.730	2.92	0.10	0.90	3nnrA	GO:0003677 GO:0006351 GO:0006355
24	0.28	0.656	3.55	0.08	0.85	2hytA	GO:0003677 GO:0006351 GO:0006355
25	0.28	0.720	2.87	0.11	0.86	3dcfA	GO:0003677 GO:0006351 GO:0006355
26	0.28	0.710	3.10	0.15	0.90	4me9A	GO:0003677 GO:0006351 GO:0006355
27	0.27	0.732	3.16	0.17	0.91	3s5rA	GO:0003677 GO:0006351 GO:0006355
28	0.27	0.690	3.44	0.14	0.90	3on4A	GO:0003677 GO:0006351 GO:0006355
29	0.26	0.560	4.12	0.14	0.80	4hkuA	GO:0003677 GO:0006351 GO:0006355
30	0.26	0.729	3.28	0.15	0.91	2wuiA	GO:0003677 GO:0006351 GO:0006355
31	0.25	0.689	3.58	0.15	0.91	2uxhA	GO:0003677 GO:0006351 GO:0006355
32	0.25	0.701	3.41	0.14	0.92	3qbmA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
33	0.24	0.723	2.93	0.13	0.90	3dewA	GO:0003677 GO:0006351 GO:0006355 GO:0016020 GO:0016021
34	0.24	0.656	3.58	0.12	0.88	4l62A	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355
35	0.23	0.599	3.78	0.10	0.81	3cjdA	GO:0003677 GO:0006351 GO:0006355
36	0.23	0.570	4.05	0.11	0.80	3bniA	GO:0003677 GO:0006351 GO:0006355
37	0.23	0.690	3.72	0.11	0.92	3lwjA	GO:0003677 GO:0006351 GO:0006355
38	0.23	0.718	3.11	0.17	0.89	5dy0A	GO:0003677 GO:0006351 GO:0006355
39	0.23	0.624	4.05	0.11	0.87	3hggA	GO:0003677 GO:0006351 GO:0006355
40	0.23	0.675	3.59	0.10	0.90	3eupA	GO:0003677 GO:0006351 GO:0006355
41	0.22	0.730	2.77	0.14	0.89	2genA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
42	0.22	0.758	2.62	0.15	0.91	4pxiB	GO:0003677 GO:0006351 GO:0006355
43	0.21	0.651	3.60	0.09	0.86	3f0cA	GO:0003677 GO:0006351 GO:0006355
44	0.21	0.653	3.48	0.18	0.87	3cdlB	GO:0003677 GO:0006351 GO:0006355
45	0.20	0.588	4.62	0.09	0.91	1rktA	GO:0003677 GO:0006351 GO:0006355
46	0.20	0.697	3.44	0.09	0.92	3rh2A	GO:0003677 GO:0006351 GO:0006355
47	0.20	0.552	4.00	0.12	0.78	2qwtA	GO:0003677 GO:0006351 GO:0006355
48	0.20	0.631	4.02	0.13	0.90	3bhqA	GO:0003677 GO:0006351 GO:0006355
49	0.19	0.714	2.83	0.14	0.88	2np5A	GO:0003677 GO:0006351 GO:0006355
50	0.19	0.629	4.14	0.11	0.88	5d18A	GO:0003677 GO:0006351 GO:0006355
51	0.19	0.716	2.91	0.15	0.90	3geuA	GO:0003677 GO:0006351 GO:0006355
52	0.19	0.638	4.12	0.12	0.93	3gziA	GO:0003677 GO:0006351 GO:0006355
53	0.19	0.695	2.74	0.17	0.84	2eh3A	GO:0003677 GO:0003700 GO:0006351 GO:0006355 GO:0046872
54	0.19	0.622	3.80	0.11	0.84	3angC	GO:0003677 GO:0006351 GO:0006355
55	0.18	0.604	4.39	0.13	0.89	2rasB	GO:0003677 GO:0006351 GO:0006355
56	0.18	0.650	3.62	0.14	0.87	2jj7B	GO:0003677 GO:0006351 GO:0006355 GO:0042802
57	0.16	0.716	3.37	0.15	0.94	5h9tH	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355 GO:0051051
58	0.16	0.675	3.36	0.10	0.87	3mvpA	GO:0003677 GO:0006351 GO:0006355
59	0.16	0.535	4.45	0.08	0.78	3b81A	GO:0003677 GO:0006351 GO:0006355
60	0.15	0.613	3.76	0.10	0.84	3ni7A	GO:0003677 GO:0006351 GO:0006355
61	0.13	0.735	3.15	0.15	0.91	1t33A	GO:0003677 GO:0003700 GO:0006351 GO:0006355
62	0.13	0.616	3.72	0.09	0.83	3zqgA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
63	0.13	0.586	3.79	0.10	0.80	3zqfA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
64	0.12	0.696	3.40	0.12	0.92	2hyjA	GO:0003677 GO:0003700 GO:0006351 GO:0006355
65	0.11	0.705	3.28	0.12	0.91	3p9tA	GO:0003677 GO:0006351 GO:0006355
66	0.10	0.585	4.00	0.06	0.82	4auxA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
67	0.08	0.629	3.79	0.11	0.87	3dpjA	GO:0003677 GO:0006351 GO:0006355
68	0.08	0.657	3.42	0.12	0.87	2fbqA	GO:0000976 GO:0003677 GO:0003700 GO:0005829 GO:0006351 GO:0006355 GO:0044212 GO:0045893 GO:0050714
69	0.07	0.619	3.85	0.07	0.87	2zcxA	GO:0003677 GO:0006351 GO:0006355
70	0.07	0.572	4.15	0.10	0.81	2vprA	GO:0003677 GO:0006351 GO:0006355 GO:0045892 GO:0046677 GO:0046872
71	0.07	0.590	4.48	0.13	0.87	2raeA	GO:0003677 GO:0006351 GO:0006355

Consensus prediction of GO terms

Molecular Function	GO:0003677	GO:0003700	GO:0042802
GO-Score	0.93	0.67	0.43
Biological Processes	GO:0045892	GO:0019217
GO-Score	0.43	0.41
Cellular Component
GO-Score

(a)	Cscore^GO is a combined measure for evaluating global and local similarity between query and template protein. It's range is [0-1] and higher values indicate more confident predictions.
(b)	TM-score is a measure of global structural similarity between query and template protein.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.
(f)	The second table shows a consensus GO terms amongst the top scoring templates. The GO-Score associated with each prediction is defined as the average weight of the GO term, where the weights are assigned based on Cscore^GO of the template.

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

Please cite the following articles when you use the I-TASSER server:
1.	J Yang, R Yan, A Roy, D Xu, J Poisson, Y Zhang. The I-TASSER Suite: Protein structure and function prediction. Nature Methods, 12: 7-8, 2015.
2.	J Yang, Y Zhang. I-TASSER server: new development for protein structure and function predictions, Nucleic Acids Research, 43: W174-W181, 2015.
3.	A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738, 2010.
4.	Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40, 2008.

I-TASSER results for job id Rv0135c

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]

[Click on result.tar.bz2 to download the tarball file including all modelling results listed on this page]