Threading Zmax Znorm MUSTER 4.05 0.70 dPPAS 6.56 0.70 wdPPAS 6.05 0.65 wMUSTER 4.28 0.74 wPPAS 5.15 0.74 dPPAS2 10.21 0.97 PPAS 5.41 0.77 Env-PPAS 4.75 0.59 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=16044) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -4.30 0.26+-0.08 16.5+-2.9 2096 0.019 model2 -4.86 1264 0.011 model3 -4.97 1162 0.009 model4 -3.63 945 0.036 model5 -4.09 838 0.023 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).