Threading Zmax Znorm MUSTER 4.92 0.85 dPPAS 8.91 0.96 wdPPAS 8.70 0.94 wMUSTER 5.54 0.95 wPPAS 5.90 0.84 dPPAS2 10.95 1.04 PPAS 6.42 0.92 Env-PPAS 5.70 0.71 ================================================================== | Estimated accuracy of your models | ================================================================== Estimated Clusters (N=13539) --------------------- ------------------ Model# C-score TM-score RMSD (A) #decoys density ------ ------- ---------- -------- ------- ------- model1 -3.38 0.34+-0.11 11.8+-4.5 2819 0.038 model2 -3.85 1897 0.024 model3 -4.65 765 0.011 model4 -4.27 749 0.015 model5 -4.67 796 0.010 C-score is a confidence score of the I-TASSER predictions which is typically in [-5,2]. TM-score and RMSD measure how close the model is to the native structure and both are estimated based on the C-score. TM-score is in [0,1] with a value >0.5 implying the model of correct topology. The TM-score and RMSD estimations are made only for the first model because absolute values of TM-score and RMSD for the lower-rank models do not strongly correlate with the C-score. The models are ranked based on the structure density of I-TASSER simulations. Please cite following articles when you use the I-TASSER Suite: 1. Y Zhang. I-TASSER server for protein 3D structure prediction. BMC Bioinformatics, 9: 40 (2008). 2. A Roy, A Kucukural, Y Zhang. I-TASSER: a unified platform for automated protein structure and function prediction. Nature Protocols, 5: 725-738 (2010). 3. J Yang, A Roy, Y Zhang. Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics, 29:2588-2595 (2013).